Tag: M.W:300-400

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, molecular formula is , belongs to piperazines compound. In a document, author is Xie, Yu, Application In Synthesis of 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid.

Scaling up microreactors for kilogram-scale synthesis of piperacillin: Experiments and computational fluid dynamics simulations

In this study, two membrane dispersion microreactors in series are used to synthesize piperacillin with low impurity content in kilogram scale. By combining experiments and computational fluid dynamics simulations, the membrane size and cross-sectional area are scaled up from 2 mm x 0.7 mm and 2 mm x 1 mm to 6.5 mm x 2.5 mm and 6.5 mm x 3.5 mm, respectively, and the reaction time is extended from similar to 10 to similar to 60 min, which achieves that the synthesis scale of each batch is increased from 15 g to 1 kg. Subsequently, the effects of distance between ammonia feed and 4-ethyl-2,3-dioxo-1-piperazine carbonyl chloride feed, pH, circulation flow rate, and dispersed phase flow rate on solution concentration are discussed. The final piperacillin product with an average yield of similar to 94.70%, a purity exceeding 99.7%, the impurity D content similar to 0.077% and E content similar to 0.045%, satisfies the requirements of pharmacopeia regarding antibiotic impurities.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5625-37-6, in my other articles. Application In Synthesis of 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Application of 111974-74-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, SMILES is [H]Cl.[H]Cl.C12=CC=CC=C1N=C(N3CCNCC3)C4=CC=CC=C4S2, belongs to piperazines compound. In a article, author is Hosseini-Ardali, Seyed Mohsen, introduce new discover of the category.

Multi-objective optimization of post combustion CO2 capture using methyldiethanolamine (MDEA) and piperazine (PZ) bi-solvent

Global warming is becoming a critical issue in 21st century which is mainly due to the growing rate of greenhouse gas emissions. This is mostly due to the large amount of CO2 emission from power generation activity using fossil fuels. One of the main methods of fighting global warming and reducing CO2 emission into atmosphere is to perform carbon capture, sequestration and utilization. Carbon capture can be performed through different ways, in which post combustion CO2 capture (PCC) has been developed and both economic and technically wise is in state of art. One of the disadvantages of PCC is its high efficiency penalty due to energy consumption in the reboiler for solvent regeneration. Many efforts have been done to reduce the consumption of energy in the reboiler via different strategies including process parameters optimization, solvent development and novel process configuration. This investigation used different blends of PZ and MDEA as solvent and process parameters optimization via evolutionary algorithm and multi-objective optimization. The optimization was performed on a conventional process flow diagram. CO2 capture efficiency and reboiler heat duty were used as the objective functions and main decision variables are solvent flowrate and MDEA/PZ concentration. Flue gas CO2 capture of 90, 91, 92, 93, and 94% corresponded to regeneration energy consumption of 2.68, 2.71, 2.72, 2.75, and 2.76 E-regen/t(CO2); respectively. These optimized values showed a higher energy efficiency compared to MEA and MDEA/PZ in conventional process configuration. (C) 2020 Elsevier Ltd. All rights reserved.

Application of 111974-74-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 111974-74-4 is helpful to your research.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, molecular formula is C8H18N2O6S2. In an article, author is Abbasi, Muhammad Athar,once mentioned of 5625-37-6, Product Details of 5625-37-6.

Synthesis of some N-sulfonated derivatives of 1-[(E)-3-phenyl-2-propenyl]piperazine as suitable antibacterial agents

In the planned research work, the nucleophilic substitution reaction of 1-[(E)-3-phenyl-2-propenyl]piperazine (1) was carried out with different sulfonyl chlorides (2a-g) at pH 9-10 to synthesize its different N-sulfonated derivatives (3a-g). The structures of the synthesized compounds were characterized by their proton-nuclear magnetic resonance (H-1-NMR), carbon-nuclear magnetic resonance (C-13-NMR) and Infra Red (IR) spectral data, along with CHN analysis. The inhibition potential of the synthesized molecules was ascertained against two bacterial pathogenic strains i.e. Bacillus subtilis and Escherichia coli. It was inferred from the results that some of the compounds were very suitable inhibitors of these bacterial strains. Moreover, their cytotoxicity was also profiled and it was outcome that most of these molecules possessed moderate cytotoxicity.

Interested yet? Keep reading other articles of 5625-37-6, you can contact me at any time and look forward to more communication. Product Details of 5625-37-6.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, molecular formula is C17H19Cl2N3S. In an article, author is Ghalib, Lubna,once mentioned of 111974-74-4, Computed Properties of C17H19Cl2N3S.

Modeling the rate of corrosion of carbon steel using activated diethanolamine solutions for CO2 absorption

A mechanistic model is developed to investigate the influence of an activator on the corrosion rate of carbon steel in the absorption processes of carbon dioxide (CO2). Piperazine (PZ) is used as the activator in diethanolamine (DEA) aqueous solutions. The developed model for corrosion takes into consideration the effect of fluid flow, transfer of charge and diffusion of oxidizing agents and operating parameters like temperature, activator concentration, CO2 loading and pH. The study consists of two major models: Vapor-liquid Equilibrium (VLE) model and electrochemical corrosion model. The electrolyte-NRTL equilibrium model was used for determination of concentration of chemical species in the bulk solution. The results of speciation were subsequently used for producing polarization curves and predicting the rate of corrosion occurring at the surface of metal. An increase in concentration of activator, increases the rate of corrosion of carbon steel in mixtures of activated DEA. (C) 2020 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights reserved.

Interested yet? Keep reading other articles of 111974-74-4, you can contact me at any time and look forward to more communication. Computed Properties of C17H19Cl2N3S.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Category: piperazines, 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, SMILES is O=S(CCN1CCN(CCS(=O)(O)=O)CC1)(O)=O, belongs to piperazines compound. In a document, author is Ebrahimiasl, Hakimeh, introduce the new discover.

Application of novel and reusable Fe3O4@Co-II(macrocyclic Schiff base ligand) for multicomponent reactions of highly substituted thiopyridine and 4H-chromene derivatives

In this research study we designed and synthesized Co-II(macrocyclic Schiff base ligand containing 1,4-diazepane) immobilized on Fe3O4 nanoparticles as a novel, recyclable, and heterogeneous catalyst. The nanomaterial was fully characterized using various techniques such as Fourier-transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray diffraction, energy-dispersiveX-ray spectroscopy, thermogravimetric analysis, vibrating sample magnetometry, differential reflectance spectroscopy, Brunauere-Emmette-Teller method, inductively coupled plasma, and elemental analysis (CHNS). Then, the catalytic performance was successfully investigated in the multicomponent synthesis of 2-amino-4-aryl-6-(phenylsulfanyl)pyridine-3,5-dicarbonitrile and 2-amino-5,10-dioxo-4-aryl-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile derivatives. Furthermore, the catalyst was isolated using a simple filtration, and recovery of the nanocatalyst was demonstrated five times without any loss of activity.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 5625-37-6. Category: piperazines.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

In an article, author is Amalorpavadoss, A., once mentioned the application of 106261-49-8, Name is 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride, molecular formula is C13H20Cl2N2O2, molecular weight is 307.22, MDL number is MFCD07772867, category is piperazines. Now introduce a scientific discovery about this category, SDS of cas: 106261-49-8.

Synthesis and characterization of piperazine containing polyaspartimides blended polysulfone membranes for fuel cell applications

A new polyaspartimide was synthesized via a Michael addition reaction of an aromatic bismaleimide (BMI) with aminoethylpiperazine (AEP) at 1:1 molar ratio. IR and NMR spectral techniques were used for the characterization of the newly synthesized polyaspartimide (PAI). The copolymer, piperazine containing polyaspartimide, was then blended with polysulfone (Psf) at 3 and 6 wt % by dissolving in the solvent DMF. The blend membranes are studied for their water uptake, ion exchange capacity, swelling ratio, chemical stability, morphology, and proton conductivity. It is observed from morphological studies that the porous structure of polysulfone has been retained even after the incorporation of PAI. The percentage water uptake of membranes of different compositions reveals that the blending of copolymer PAI with polysulfone enhances the water uptake nature of the membrane. The chemical stability on membranes revealed that Psf/PAI-6% has a degradation of about 2.26% which is much lower than that of neat Psf membranes (3.43%), higher chemical stability. The neat Psf found to have an IEC value of 8.045 mmol/g and the IEC values increase with the addition of PAI. The highest value of IEC is obtained for the 6% PAI loaded Psf blend membrane with a value of 8.235 mmol/g. The study on the capacity of proton exchange has proved that the copolymer blend membrane is given higher proton conductivity to the extent of 4.09 x 10(-4) S cm(-1).

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 106261-49-8, SDS of cas: 106261-49-8.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, SMILES is O=S(CCN1CCN(CCS(=O)(O)=O)CC1)(O)=O, belongs to piperazines compound. In a document, author is Taniguchi, Ikuo, introduce the new discover, Computed Properties of C8H18N2O6S2.

Piperazine-immobilized polymeric membranes for CO2 capture: mechanism of preferential CO2 permeation

Amines are incorporated into various membranes to improve their CO2 separation performance. With amine-containing polymeric membranes, gas transport properties are often enhanced under humidity, where CO2 migrates through the membranes in the form of bicarbonate ions. Piperazine (Pz) and its derivatives are known to catalyze the conversion of CO2 to bicarbonate ions and have been used in liquid amine scrubbing technology. Piperazines were immobilized in poly(vinyl alcohol) (PVA), and the resulting polymeric membranes showed high CO2 separation performance over H-2 and CH4. The gas transport properties were dependent on the chemical structure of the amines. In particular, 3-(1-piperazinyl)-1,2-propanediol (PzPD)-containing polymeric membranes gave excellent CO2 separation performance, and the CO2 permeability and CO2 selectivity over CH4 were 1060 Barrer and 370, respectively, at 50 degrees C and 90% relative humidity with a transmembrane CO2 pressure of 11 kPa. The interaction between PzPD and CO2 was quantitatively studied by inverse-gate decoupling C-13 NMR spectroscopy. CO2 interacted with the secondary amino group on the Pz ring to form a carbamate, which was readily hydrolyzed to produce bicarbonate ions. The hydroxyl group on the C2 carbon of PzPD facilitated the interaction between CO2 and the amine through hydrogen bonding, resulting in enhanced diffusivity of CO2 in the membranes.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5625-37-6 is helpful to your research. Computed Properties of C8H18N2O6S2.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Product Details of 111974-74-4, 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, molecular formula is C17H19Cl2N3S, belongs to piperazines compound. In a document, author is Zhang, Li, introduce the new discover.

Design, synthesis and biological evaluation of novel osthole-based derivatives as potential neuroprotective agents

A total of 26 compounds based on osthole skeleton were designed, synthesized. Their cytoprotective abilities of antioxidation, anti-inflammation and A beta(42)(Amyloid beta-protein 42)-induced neurotoxicity were evaluated by MTT assays. Mechanism of the action of selected compounds were investigated by molecular docking. AlogP, logS and blood-brain barrier (BBB) permeability of all these compounds were simulated by admetSAR. Most of the compounds showed better antioxidative and anti-inflammatory activities compared with osthole, especially OST7 and OST17. The compound OST7 showed relative high activity in neuroprotection against H2O2 (45.7 +/- 5.5%), oxygen glucose deprivation (64.6 +/- 4.8%) and A beta(42) (61.4 +/- 5.2%) at a low concentration of 10 mu M. EC50 of selected compounds were measured in both H2O2 and OGD induced cytotoxicity models. Moreover, NO inhibiting ability of OST17(50.4 +/- 7.1%) already surpassed the positive drug indomethacin. The structure activity relationship study indicated that introduction of piperazine group, tetrahydropyrrole group and aromatic amine group might be beneficial for enhancement of osthole neuroprotective properties. Molecular docking explained that the reason OST7 exhibited relatively stronger neuroprotection against A beta because of the greater area of interactions between molecule and target protein. OST7 and OST17 both provided novel methods to investigate osthole as anti-AD drugs.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 111974-74-4. Product Details of 111974-74-4.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 106261-49-8, Name is 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride, SMILES is Cl.Cl.CN1CCN(CC1)CC2=CC=C(C(=O)O)C=C2, in an article , author is Kettenmann, Sebastian Doniz, once mentioned of 106261-49-8, Name: 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride.

Copper(II) Complexes with Tetradentate Piperazine-Based Ligands: DNA Cleavage and Cytotoxicity

Five-coordinate Cu(II) complexes, [Cu(L-n)X]ClO4/PF6, where L-n = piperazine ligands bearing two pyridyl arms and X = ClO4- for L-n = L-1 (1-ClO4), L-2 (2-ClO4), L-3 (3-ClO4), and L-6 (6-ClO4) as well as [Cu(L-n)Cl]PF6 for L-n = L-1 (1-Cl), L-4 (4-Cl), and L-5 (5-Cl) have been synthesized and characterized by spectroscopic techniques. The molecular structures of the last two complexes were determined by X-ray crystallography. In aqueous acetonitrile solutions, molar conductivity measurements and UV-VIS spectrophotometric titrations of the complexes revealed the hydrolysis of the complexes to [Cu(L-n)(H2O)](2+) species. The biological activity of the Cu(II) complexes with respect to DNA cleavage and cytotoxicity was investigated. At micromolar concentration within 2 h and pH 7.4, DNA cleavage rate decreased in the order: 1-Cl approximate to 1-ClO4 > 3-ClO4 >= 2-ClO4 with cleavage enhancements of up to 23 million. Complexes 4-Cl, 5-Cl, and 6-ClO4 were inactive. In order to elucidate the cleavage mechanism, the cleavage of bis(4-nitrophenyl)phosphate (BNPP) and reactive oxygen species (ROS) quenching studies were conducted. The mechanistic pathway of DNA cleavage depends on the ligand’s skeleton: while an oxidative pathway was preferable for 1-Cl/1-ClO4, DNA cleavage by 2-ClO4 and 3-ClO4 predominantly proceeds via a hydrolytic mechanism. Complexes 1-ClO4, 3-ClO4, and 5-Cl were found to be cytotoxic against A2780 cells (IC50 30-40 mu M). In fibroblasts, the IC50 value was much higher for 3-ClO4 with no toxic effect.

Interested yet? Read on for other articles about 106261-49-8, you can contact me at any time and look forward to more communication. Name: 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

In an article, author is Jia, Zehui, once mentioned the application of 111974-74-4, SDS of cas: 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, molecular formula is C17H19Cl2N3S, molecular weight is 368.3239, MDL number is MFCD08703302, category is piperazines. Now introduce a scientific discovery about this category.

Rapid degradation of ciprofloxacin over BiOCl: Insight into the molecular structure transformation and antibacterial activity elimination

Currently, the widespread usage of antibiotics brings great challenge to sustainable water environment due to the production of drug-resistant bacteria, the rapid and effective removal of antibiotics attracts more and more attention. Herein, a BiOCl microsphere prepared by a facile hydrolysis method via controlling the EG-H2O ratio was found to have unexpected photocatalytic activity for ciprofloxacin (CIP) removal. The photodegradation rate of CIP over optimal BiOCl-20 reached 92.9% in only 3 min of simulated sunlight irradiation, and the mineralization rate was 30.8% after 60 min reaction. The antibacterial tests of CIP solution under different irradiation minutes were evaluated using Escherichia coli (E. coli) as the model bacteria. The results indicated that CIP photodegradation intermediates had also certain antimicrobial potency, which could be eliminated almost completely after 3 min irradiation, although there still had some incompletely mineralized intermediates. In view of these results, the macroscopic degradation behavior of CIP over BiOCl-20 as well as the microscopic existence state and reaction behavior of the intermediates should be clarified. A ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was employed for determination of CIP and its intermediates. Ten primary intermediates were separated and identified, and their corresponding molecular structures were elucidated. Three main photodegradation pathways were deduced, and the correlation between molecular structure transformation and antibacterial activity of CIP was established. Because of the destruction of piperazine ring and defluorination of quinolone ring, the antibacterial activity of the treated CIP solution was weakened or even eliminated. Finally, a possible photodegradation mechanism was proposed, the OVs, O-center dot(2)-, h(+) and (OH)-O-center dot played significant roles in the CIP photodegradation. This work does have great perspective for BiOCl potential application in CIP wastewater treatment.

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics