Tag: M.W:200-300

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about Favored formation of an O-glycoside during ribosidation of 5-methyl-2-(methylthio)-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one.Formula: C7H15BrO2.

Condensing (±)-(EtO)2CHMeCHCH(CN)CO2Et and thiourea gave pyrimidine I. Alkylating I at 2-SH group with Me2SO4 followed by ring closure gave pyrrolo[2,3-d] pyrimidine II (R = Me, R1 = H) (III). Silylating III and then treating with 2,3,5-tri-O-acetyl-1-bromo-D-ribofuranose in the presence of Hg(II) salts gave nucleoside IV (R = Ac), not the N-7-glycoside from ribosidation of 2-(methylthio)-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one. Hydrolysis of IV (R = Ac) under mild conditions gave IV (R = H), which had a UV spectrum similar to II (R = R1 = Me) down to pH 2. At a lower pH hydrolysis of the glycosidic bond occurs.

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In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Pyrazine derivatives. I. 2-Hydroxy-3,6-dimethylpyrazine, published in 1947, which mentions a compound: 3400-55-3, Name is 2-Bromopriopionaldehydediethylacetal, Molecular C7H15BrO2, Reference of 2-Bromopriopionaldehydediethylacetal.

An examination of the methods for the synthesis of 2-hydroxypyrazines was undertaken with the object of synthesizing deoxyaspergillic acid (Part II). MeCH(NH2)CHO.HCl is a resinlike salt which could not be condensed with MeCHBrCOBr. MeCHBrCHO yields 63-4% MeCHBrCH(OEt)2 (I), b14 63-4°. I (70 g.) and 134 g. NH3 in 500 g. absolute EtOH, heated 7.5 h. at 125-30°, give 39% MeCH(NH2)CH(OEt)2 (II), b21 66°. II (7.45 g.) and 5.1 g. 4-methylmorpholine in 50 cc. CHCl3 at 0°, treated dropwise (30 min.) with 10.8 g. MeCHBrCOBr in 50 cc. CHCl3, with stirring for an addnl. hr. (during which the reaction mixture warmed to room temperature), give 11 g. α-(α-bromopropionylamino) propionaldehyde di-Et acetal, m. 56.5-7°; this could not be hydrolyzed to the aldehyde and could not be converted directly to 2-hydroxy-3,6-dimethylpyrazine (III). II (18 g.) in 10 cc. H2O, treated successively at 0° with 80 cc. concentrated HCl and 30 cc. EtSH, the mixture kept 24 h. at room temperature, poured into 200 cc. 40% NaOH and 500 g. ice, and the oil extracted with CHCl3, gives 73% α-aminopropionaldehyde di-Et mercaptal (IV), b3 105° (picrate, m. 153-4°). IV (19.5 g.), 15 g. butylpiperidine, and 50 cc. CHCl3 at 0°, treated dropwise with 25 g. MeCHBrCOBr in 50 cc. CHCl3, give 31 g. (crude) α-(α-bromopropionylamino) propionaldehyde di-Et mercaptal (V), m. 47-8°, slowly decompose on standing in air. V (3.14 g.) and 10 g. CdCO3 in 50 cc. EtOH and 10 cc. H2O, stirred 24 h. with 5.6 g. HgCl2 in 50 cc. EtOH, the filtrate saturated with NH3 at 0°, allowed to stand 48 h., the filtrate evaporated to dryness, and extracted with C6H6, give 250 mg. III, m. 210-11° (picrate, m. 181-5°). 2-Amino-3,6-dimethylpyrazine (20% yield) with NaNO2 in N HCl gives 60% III. 2-Aminopyrazine yields 30% 2-hydroxypyrazine, m. 187-8° [the brilliant yellow color observed by Weijland, et al. (C.A. 39, 3001.2) must be due to an impurity].

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Synthetic Route of C7H15BrO2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about (Alkylthio)bis(alkylsulfonyl)- and tris(alkylthio)propanes. Author is Boehme, H.; Russmann, H..

(RSO2)2C-Me Na+ (R = Me, Et), formed in situ from (RSO2)2CHMe and Na in dioxane, reacted with R1SCH2Cl (R1 = Me, Et) to give (RSO2)2CMeCH2SR1, oxidation of which gave (RSO2)2CMeCH2SO2R1. Reaction of (MeSO2)2C-H Na+ with MeSCH2Cl gave [(MeSO2)2CH]2CH2 and (MeSO2)2C(CH2SMe)2, which was oxidized to give (MeSO2)2C(CH2SO2Me)2. Condensation of MeSH with MeCOCH2SMeHCl and BrCHMeCH(OEt)2-HBr yielded (MeS)2CMeCH2SMe (I) and (MeS)2CHCHMeSMe (II), resp. A 3:2 I-II mixture was obtained by condensation of MeSH with MeOCH2COMe and HCl.

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Application of 18583-60-3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Potassiumtris(1-pyrazolyl)borohydride, is researched, Molecular C9H10BKN6, CAS is 18583-60-3, about Platinum-tin bonded complexes, including a structural analysis of the octahedral tris(pyrazol-1-yl)borate complex Pt(SnMe3)Me2{(pz)3BH-N,N’,N””}. Author is Canty, Allan J.; Jin, Hong; Skelton, Brian W.; White, Allan H..

The platinum(II) complex K[PtMe2{(pz)3BH-N,N’}] reacts with SnCl2Me2 to form Pt(SnClMe2)Me2{(pz)3BH-N,N’,N””} ([(pz)3BH]- = tris(pyrazol-1-yl)borate). The closely related complex Pt(SnMe3)Me2{(pz)3BH-N,N’,N””} has distorted octahedral geometry for platinum with Pt-Sn 2.5727(8) Å. The Pt-N distance trans to the SnMe3 group [2.237(7) Å] is longer than those trans to the Me groups [2.127(7) and 2.131(6) Å], indicating for the trimethylstannyl group a trans influence which is higher than that for the Me group.

Although many compounds look similar to this compound(18583-60-3)Application of 18583-60-3, numerous studies have shown that this compound(SMILES:[BH-](N1N=CC=C1)(N2N=CC=C2)N3N=CC=C3.[K+]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

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Piperazine – Wikipedia,
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Synthetic Route of C7H6BrI. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-(Bromomethyl)-4-iodobenzene, is researched, Molecular C7H6BrI, CAS is 16004-15-2, about Synthesis of 1,2,3-triazole benzophenone derivatives and evaluation of in vitro sun protection, antioxidant properties, and antiproliferative activity on HT-144 melanoma cells. Author is Dias, Maria C. F.; de Sousa, Bianca L.; Ionta, Marisa; Teixeira, Robson R.; Goulart, Thiago Q.; Ferreira-Silva, Guilherme A.; Pilau, Eduardo J.; dos Santos, Marcelo H..

Two series of 1,2,3-triazole-benzophenone derivatives I [R = R1 = Ph, 3-MeC6H4, 4-ClC6H4, etc.] and II [R2 = Ph, 2-pyridyl, 4-BrC6H4, etc.] were synthesized and their antioxidant, anticancer and photoprotective effects evaluated. For the compounds synthesis, 4,4′-dihydroxybenzophenone and 2,4-dihydroxybenzophenone were propargylated and afforded alkynes, bis(4-(prop-2-yn 1-yloxy))benzophenone and (2-hydroxy-4-(prop-2-yn-1-yloxy))benzophenone, resp. The copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction between the alkynes and several benzyl azides gave the compounds I and II with yields ranging from 35 to 95%. Compounds I and II at the concentration of 0.2μg mL-1 (a no-cytotoxic concentration) exhibited a solar protection factor (SPF) comparable to pos. control benzophonen-3 (BP-3). Concerning their antioxidant and cytotoxic effects, the derivatives from 2,4-dihydroxybenzophenone showed high in vitro antioxidant effects as well as cytotoxicity against A549 (lung carcinoma), MCF-7 (breast carcinoma) and HT-144 (metastatic melanoma) cell lines, without significant cytotoxicity to a non-cancerous cell line. Derivatives II [R2 = Ph, 4-MeC6H4, 2,4-F2C6H3] induced cell death and cell cycle arrest at G1/S in HT-144 melanoma cells.

Although many compounds look similar to this compound(16004-15-2)Synthetic Route of C7H6BrI, numerous studies have shown that this compound(SMILES:IC1=CC=C(CBr)C=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

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Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Gemel, Christian; John, Roland; Slugovc, Christian; Mereiter, Kurt; Schmid, Roland; Kirchner, Karl published an article about the compound: Potassiumtris(1-pyrazolyl)borohydride( cas:18583-60-3,SMILESS:[BH-](N1N=CC=C1)(N2N=CC=C2)N3N=CC=C3.[K+] ).Synthetic Route of C9H10BKN6. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:18583-60-3) through the article.

[Ru(η6-p-MeC6H4Pri)Cl2]2 reacted with K[quin] (quin = quinolin-8-olate) to yield the half-sandwich complex Ru(η6-p-MeC6H4Pri)(quin)Cl 1. Chloride abstraction from 1 with AgCF3SO3 affords the neutral complex Ru(η6-p-MeC6H4Pri)(quin)(κ1O-CF3SO3). The lability of the CF3SO3- ligand in 2 is apparent by the reaction with MeCN giving [Ru(η6-p-MeC6H4Pri)(quin)(MeCN)]CF3SO3 3. Refluxing RuTp(COD)Cl in the presence of K[quin] gave Ru(COD)(quin)2 4 containing no Tp ligand; 4 also was obtained in good yield by treating [Ru(COD)Cl2]n with K[quin] in boiling MeOH. Treatment of either 1 or 3 with 1 equiv of KTp gave the unusual complex Ru(η6-p-MeC6H4Pri)(quin)(κ1N-Tp) (5) featuring a κ1-coordinated Tp ligand. However, if 1 is treated with KTp in the presence of AgCF3SO3 the cationic complex [Ru(η6-p-MeC6H4Pri)(quin)(κ1-Hpz)]CF3SO3 6 was obtained containing a pyrazole ligand as a result of B-N bond cleavage. Complexes 1, 4, 5, and 6 were characterized by x-ray crystallog.

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Xing, Na; Shan, Hui; Tian, Xing; Yao, Qiang; Xu, Li-Ting; Xing, Yong-Heng; Shi, Zhan published the article 《Two new scorpionate oxomolybdenum(VI)-poly(pyrazolyl)borate complexes: synthesis, structure, and catalytic performance in the oxidation of cyclohexane》. Keywords: oxomolybdenum polypyrazolylborate complex preparation oxidation cyclohexane crystal structure.They researched the compound: Potassiumtris(1-pyrazolyl)borohydride( cas:18583-60-3 ).Name: Potassiumtris(1-pyrazolyl)borohydride. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:18583-60-3) here.

Two new oxomolybdenum(VI) complexes [(TpMoO2)2(μ-O)]·H2O (1) and (Tp4-IMoO2)2(μ-O) (2) were synthesized and characterized by elemental anal., IR spectra, UV-Vis spectroscopy, powder X-ray diffraction, single-crystal X-ray diffraction and thermogravimetric analyses (TG). In addition, the catalytic performances of complexes 1 and 2 were studied firstly on the oxidation reaction of cyclohexane at room temperature

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Piperazine – Wikipedia,
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Synthetic Route of C7H6BrI. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-(Bromomethyl)-4-iodobenzene, is researched, Molecular C7H6BrI, CAS is 16004-15-2, about Lithographic patterning of ferromagnetic FePt nanoparticles from a single-source bimetallic precursor containing hemiphasmidic structure for magnetic data recording media. Author is Meng, Zhengong; Ho, Cheuk-Lam; Wong, Hon-Fai; Yu, Zhen-Qiang; Zhu, Nianyong; Li, Guijun; Leung, Chi-Wah; Wong, Wai-Yeung.

Patterning of L10 FePt nanoparticles (NPs) with high coercivity offers a promising route to develop bit-patterned media (BPM) for the next generation magnetic data recording system, but the synthesis of monodisperse FePt NPs and mass production of their nanopatterns has been a long-standing challenge. Here, highly efficient nanoimprint lithog. was applied for large-scale universal patterning, which was achieved by imprinting the solution of a single-source bimetallic precursor. The rigid coplanar metallic cores and the surrounding flexible tails in the bimetallic complex permit the spontaneous mol. arrangements to form the highly ordered neg. morphol. replicated from the soft template. In-situ pyrolysis study was then investigated by one-pot pyrolysis of the precursor under an Ar/H2 atmosphere, and the resultant NPs were fully characterized to identify the phase, morphol. and magnetic properties. Finally, highly-ordered patterns on certain substrates were preserved perfectly after pyrolysis and could be potentially utilized in magnetic data recording media.

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Piperazine – Wikipedia,
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Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Potassiumtris(1-pyrazolyl)borohydride, is researched, Molecular C9H10BKN6, CAS is 18583-60-3, about Enantiocontrolled Synthesis of 2,3,6-Trisubstituted Piperidines Using (η3-Dihydropyridinyl)molybdenum Complexes as Chiral Scaffolds. Total Synthesis of (-)-Indolizidine 209B.Safety of Potassiumtris(1-pyrazolyl)borohydride.

Enantiopure TpMo(CO)2(pyridinyl) complexes were prepared using an efficient and scalable enzymic kinetic resolution of the precursor to the molybdenum complex. A single TpMo(CO)2(pyridinyl) complex can function as a chiral scaffold for the enantiocontrolled synthesis of either 2,3,6-cis- or 2,6-cis-3-trans-trisubstituted piperidines. The synthetic potential of this methodol. was demonstrated by a total synthesis of (-)-indolizidine 209B.

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Synthetic Route of C7H15BrO2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about Competitive processes in the hydration of dicarbonyl η5-(cyclopentadienyl) alleneiron cations. Author is Klemarczyk, Philip; Rosenblum, Myron.

Hydration of CpFe(CO)2(CH2:C:CH2) under acidic conditions gives a mixture of CpFe(CO)2CH2COMe and CpFe(CO)2CHMeCHO. The aldehyde complex is derived by acid-catalyzed rearrangement of an allyl alc. complex in a process involving a metal-stabilized cation.

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