Category: piperazines

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, molecular formula is , belongs to piperazines compound. In a document, author is Zhang, Dandan, Category: piperazines.

Photocatalytic degradation of ofloxacin by perovskite-type NaNbO3 nanorods modified g-C3N4 heterojunction under simulated solar light: Theoretical calculation, ofloxacin degradation pathways and toxicity evolution

Graphitic carbon nitride (g-C3N4) is widely used as a visible-light-driven photocatalyst but limited by the rapid photoexcited electron-hole pairs recombination rate. To promote the photocatalytic activity of g-C3N4, a class of heterojunction photocatalysts, perovskite-type sodium niobate (NaNbO3) nanorods modified g-C3N4 (SNCN), was fabricated through a two-step hydrothermal and thermal polymerization method in this study. X-ray powder diffraction (XRD), transmission electron microscope (TEM) and X-ray photoelectron spectroscopy (XPS) demonstrated the successful decoration of NaNbO3 onto g-C3N4, as well as the formation of material interface with high reactivity. The optimal material (SNCN-3) exhibited an extremely high degradation efficiency of ofloxacin (OFL) under simulated solar light, as the kinetic rate constant (k) was 29.6 and 10.4 times of that for the neat g-C3N4 and NaNbO3, respectively. Energy band structure analysis indicated that SNCN-3 was a type II heterojunction. Moreover, surface photovoltage (SPV), photoluminescence (PL) and transient photocurrent response measurements confirmed SNCN-3 had the highest electron-hole separation efficiency compared with NaNbO3, g-C3N4 and the other SNCN composites. Quenching tests indicated that O-center dot(2)- and holes were the primary reactive species for OFL degradation. Density functional theory (DFT) calculation on further revealed the atoms of OFL with high Fukui index (f(0)) preferred to be attacked by the produced radicals. Cleavage of piperazine moiety and substitution of F were the key OFL degradation pathways. In addition, the reduced toxicity of transformation products after photocatalysis verified the proposed technique was a green method. This work provided the promising application of g-C3N4/NaNbO3 heterojunction photocatalysts for degradation of antibiotic pollutants in water.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5625-37-6, in my other articles. Category: piperazines.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Name: 4-(4-Methylpiperazin-1-yl)phenylamine, 16153-81-4, Name is 4-(4-Methylpiperazin-1-yl)phenylamine, SMILES is NC1=CC=C(N2CCN(C)CC2)C=C1, in an article , author is Park, Hee Min, once mentioned of 16153-81-4.

Preparation and characterization of TFC NF membrane with improved acid resistance behavior

In this study, we prepared the novel acid-resistant thin-film composite (TFC) piperazine(PIP)-based nanofiltration (NF) membrane using melamine (Mel), sulfonated-melamine formaldehyde (SMF), and sulfanilamide (SA) through interfacial polymerization on a polysulfone (PSf) support layer. A long-term acid-resistant experiment for divalent salt was carried out with static immersion tests in a 15 wt% sulfuric acid solution. The divalent rejection of the PIP1-SMF0.3-SA(0.05) in a 15 wt% sulfuric acid solution was maintained at over 96% after 10 days, and then slightly decreased to 94% for 20 days, and finally was maintained over 90% for 30 days. The flux was maintained at about 20 GFD even after 30 days of immersion in acid. In order to confirm the degree of hydrolysis in amide, the bond dissociation energy (BDE) was calculated using the density functional theory (DFT). BDE values of PIP-TMC, Mel-TMC, and SA-TMC were 79.34, 83.78, and 93.91 kcal/mol. Consequently, PIP1-SMF0.3-SA(0.05) having s-triazine and sulfonyl amide group exhibited acid-stable performance because the C-N bond is more stable and the slow hydrolysis reaction in acid. Our research for preparing high perm-selectivity and long-term acid stability membrane can extend NF technology in many industries, particularly in the recovery of rare metals from acidic solutions.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 16153-81-4, you can contact me at any time and look forward to more communication. Name: 4-(4-Methylpiperazin-1-yl)phenylamine.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Electric Literature of 130307-08-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 130307-08-3, Name is 1-(4-Bromophenyl)-4-methylpiperazine, SMILES is CN1CCN(C2=CC=C(Br)C=C2)CC1, belongs to piperazines compound. In a article, author is Wang, Wenduo, introduce new discover of the category.

Flame retardancy, thermal decomposition and mechanical properties of epoxy resin modified with copper N, N’-piperazine (bismethylene phosphonate)

A metal-organic phosphonate, i.e., copper N, N’-piperazine (bismethylene phosphonate) (CuPB) was synthesized and utilized to modify epoxy resin (EP). The flame retardancy, thermal decomposition and mechanical properties of EP/CuPB composites are overall evaluated, and the mechanism is tentatively discussed. The results reveal that EP containing 3.0 wt% CuPB (EP/CuPB-3) passes UL-94 V-0 grade with an increased limiting oxygen index of 28.5%. The peak heat release rate, total heat release, total smoke release and peak CO production rate of EP/CuPB-3 in cone calorimeter test are, respectively, reduced by 43.5%, 28.0%, 37.3% and 51.9%, compared to that of pure EP. Besides, a decreased mass-loss rate (16.2% min(-1)) and an increased char yield (26.8%) of EP/CuPB-3 in the thermogravimetric analysis are achieved as a result of the char-promotion function of CuPB. Satisfactorily, the thermal resistance of EP/CuPB composites is slightly improved with an increased glass transition temperature, and the mechanical properties including tensile and impact strengths are not much affected.

Electric Literature of 130307-08-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 130307-08-3 is helpful to your research.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, molecular formula is C17H19Cl2N3S, belongs to piperazines compound. In a document, author is Chen, Hong, introduce the new discover, COA of Formula: C17H19Cl2N3S.

Novel piperazine-containing oligomer as flame retardant and crystallization induction additive for thermoplastics polyurethane

In flame-retarding polymer field, it is very difficult to achieve simultaneous outstanding flame retardancy and excellent mechanical properties, thus causing the serious lack of high-performance flame-retarded polymers. In this work, a novel piperazine-containing additive with phosphorus and alkynyl, named poly (2-butyne-1,4-diol piperazine bisphosphonate) (PPBPP), was designed to fabricate flame-retarding high-performance thermoplastics polyurethane (TPU). Experimental results showed that 3.0 wt% PPBPP endowed TPU with a UL-94 V-0 rating in burning test, and the melt dripping of TPU disappeared at 12.0 wt% PPBPP. More importantly, mechanical properties of flame-retarding TPU/PPBPP remarkably recovered with increasing the PPBPP, and the elongation at break for TPU containing 12 wt% PPBPP reached 812.1%, be almost equivalent to that of pure TPU, which is totally different that occurred in traditional flame-retarding TPU system. The study on mechanical recovery mechanism demonstrated that the PPBPP-induced crystallization of TPU made up for the destruction of PPBPP to hydrogen bonding in the hard segment domain of TPU and the following mechanical loss of matrix, leading to the remarkable recovery in mechanical properties of flame-retarding TPU. The study on the flameretardant mechanism illustrated that alkynyl in PPBPP underwent crosslinking process during heating, and the formed network structure joined the charring of phosphorus-nitrogen flame retardant and effectively promoted the condensed-phase flame-retardant efficiency of PPBPP and anti-melt dripping performance of TPU/PPBPP. This work proposed an efficient route for fabricating flame-retarding high-performance TPU, namely, introduction of piperazine groups into functional flame retardant compensates for the damage of additive to mechanical properties via the induced crystallization and then achieves simultaneously flame retardation and high performance of TPU.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 111974-74-4. COA of Formula: C17H19Cl2N3S.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, HPLC of Formula: C17H19Cl2N3S, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 111974-74-4, Name is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride, molecular formula is C17H19Cl2N3S. In an article, author is Shinde, Ravindra R.,once mentioned of 111974-74-4.

Synthesis and antimicrobial activity of 2-(4-(benzo[d]thiazol-5-ylsulfonyl)piperazine-1-yl)-N-substituted acetamide derivatives

A new series of 2-(4-(benzo[d]thiazol-5-ylsulfonyl)piperazin-1-yl)-N-substituted acetamide(5a-5k)compounds have been synthesized, and these compounds were characterized with spectral data like IR, NMR, and Mass spectroscopy. All compounds were evaluated in vitro for their efficacy as antimicrobial against Gram-positive and Gram-negative pathogenic bacterial strains such asStaphylococcus aureus, Bacillus subtilis, Escherichia coliandPseudomonas aeruginosausing ciprofloxacin as a standard and fungal strains likeCandida albicansandAspergillus fumigatusas compared with standard drug Clotrimazole, and Molecular docking study shows that all these compounds were having good to excellent correlation binding energy as compared with binding energy of standard drugs.

If you¡¯re interested in learning more about 111974-74-4. The above is the message from the blog manager. HPLC of Formula: C17H19Cl2N3S.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5308-25-8, Name is 1-Ethylpiperazine, SMILES is CCN1CCNCC1, in an article , author is Hakobyan, N. Z., once mentioned of 5308-25-8, Application In Synthesis of 1-Ethylpiperazine.

Synthesis and Antitumor Activity of Piperazine-Based Tertiary Amino Alcohols and Their Dihydrochlorides

Aminomethylation of 1-(4-alkoxyphenyl)-2-phenyl(chlorophenyl)ethanones with paraformaldehyde and substituted piperazines in ethanol furnished 1-(4-alkoxyphenyl)-3-(4-R-piperazin-1-yl)-2-phenyl (chlorophenyl)propan-1-ones. Reaction of the latter with alkyl (aryl) magnesium halides resulted in the formation of tertiary amino alcohols of piperazine series, which were further converted to dihydrochlorides. The effect of synthesized compounds on the processes of tumor DNA methylationin vitrowas studied.

Interested yet? Read on for other articles about 5308-25-8, you can contact me at any time and look forward to more communication. Application In Synthesis of 1-Ethylpiperazine.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 5294-61-1, Name is N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide, molecular formula is , belongs to piperazines compound. In a document, author is Li, Shi, Formula: C14H21N3O.

Ultra-low pressure cellulose-based nanofiltration membrane fabricated on layer-by-layer assembly for efficient sodium chloride removal

Cellulose is a renewable, biodegradable, biocompatible, and sustainable material. A bamboo cellulose-based nanofiltration membrane (LBL-NF-CS/BCM) was prepared with a combination of layer-by-layer assembly and spraying methods. The chemical structure, morphology, and surface charge of the resultant LBL-NF-CS/BCM composite membranes were characterized based on Thermo Gravimetric Analysis (TGA), X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), and X-ray Photoelectron Spectroscopy Scanning (XPS). The nanofiltration performance of the LBL-NF-CS/BCM composite membranes was evaluated using 500 ppm NaCl solutions under 0.3 MPa pressure. It was found that the LBL-NF-CS/BCM composite membranes had a rejection rate of about 36.11 % against a 500 ppm NaCl solution under the conditions tested, and membrane flux of about 12.08 L/(m(2) h) was reached. The combined layer-by-layer assembly and spraying provides a scalable and convenient process concept for nanofiltration membrane fabrication.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5294-61-1, in my other articles. Formula: C14H21N3O.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Related Products of 16153-81-4, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 16153-81-4, Name is 4-(4-Methylpiperazin-1-yl)phenylamine, SMILES is NC1=CC=C(N2CCN(C)CC2)C=C1, belongs to piperazines compound. In a article, author is Mahmoud, Mohamed E., introduce new discover of the category.

Water-stable metal-organic framework/amine-modified silica/poly (piperazine-cresol) hybrids for efficient uptake of La(III) ions

Hybrid nanocomposites of polymers and metal organic frameworks (MOFs) are characterized by distinctive surface activity due to high surface area of MOFs, excellent carrier nature and good thermal stability polymers. The combined two materials are expected to perform unusual performance in adsorptive removal and extraction processes. Therefore, microporous MOFs/polymer hybrid nanocomposite, Zn(Glu)-SiNH/PPC, has been synthesized by direct linking between silica-amine modified MOFs (Zn(Glu)-SiNH2) with poly(piperazine-cresol) (PPC) via microwave irradiation heating. Characterizations of Zn(Glu)-SiNH/PPC hybrid nanocomposite were explored by various techniques as XRD, surface area, SEM, TEM, and FT-IR. Lanthanum (III) ion was chosen as an example of the lanthanides series to investigate its adsorption activity by Zn(Glu)-SiNH/PPC hybrid nanocomposite. The maximum uptake capacity (15023.0 mu mol g(-1)) was established under the optimum conditions (pH 7.0, 20 min and 5 mg of Zn(Glu)-SiNH/PPC). The recognized equilibrium data of La(III) adsorption onto Zn(Glu)-SiNH/PPC hybrid nanocomposite were well explained by the Langmuir model. Additionally, the kinetics study was fitted satisfactorily with the pseudo-second order model. The recovery of La(III) ions from water samples (tap, sea and waste) were recognized as 98.23, 98.28 and 99.66%, respectively.

Related Products of 16153-81-4, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 16153-81-4 is helpful to your research.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Application of 16153-81-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 16153-81-4, Name is 4-(4-Methylpiperazin-1-yl)phenylamine, SMILES is NC1=CC=C(N2CCN(C)CC2)C=C1, belongs to piperazines compound. In a article, author is Wieczorek, Dorota, introduce new discover of the category.

Synthesis and Influence of 3-Amino Benzoxaboroles Structure on Their Activity against Candida albicans

Benzoxaboroles emerged recently as molecules of high medicinal potential with Kerydin(R) (Tavaborole) and Eucrisa(R) (Crisaborole) currently in clinical practice as antifungal and anti-inflammatory drugs, respectively. Over a dozen of 3-amino benzoxaboroles, including Tavaborole’s derivatives, have been synthetized and characterized in terms of their activity against Candida albicans as a model pathogenic fungus. The studied compounds broaden considerably the structural diversity of reported benzoxaboroles, enabling determination of the influence of the introduction of a heterocyclic amine, a fluorine substituent as well as the formyl group on antifungal activity of those compounds. The determined zones of the growth inhibition of examined microorganism indicate high diffusion of majority of the studied compounds within the applied media as well as their reasonable activity. The Minimum Inhibitory Concentration (MIC) values show that the introduction of an amine substituent in position 3 of the benzoxaborole heterocyclic ring results in a considerable drop in activity in comparison with Tavaborole (AN2690) as well as unsubstituted benzoxaborole (AN2679). In all studied cases the presence of a fluorine substituent at position para to the boron atom results in lower MIC values (higher activity). Interestingly, introduction of a fluorine substituent in the more distant piperazine phenyl ring does not influence MIC values. As determined by X-ray studies, introduction of a formyl group in proximity of the boron atom results in a considerable change of the boronic group geometry. The presence of a formyl group next to the benzoxaborole unit is also detrimental for activity against Candida albicans.

Application of 16153-81-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 16153-81-4.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 5308-25-8, Name is 1-Ethylpiperazine, formurla is C6H14N2. In a document, author is Zhang, Gang, introducing its new discovery. Safety of 1-Ethylpiperazine.

Molecular Insight into the Discrepancy of Antitubercular Activity between 8-Nitro and 8-Cyano Benzothiazinones

Benzothiazinones with 8-NO2 group is a novel class of compounds with potent antitubercular activity, especially BTZ043 and PBTZ169, which covalently inhibit DprE1. 8-CN benzothiazinones is reported as another type of benzothiazinones with potent antitubercular activity. Taking this as the starting point, a series of 8-CN benzothiazinones are synthesized and evaluated for their antitubercular activity. To better understand the antitubercular activity of this series of benzothiazinones, the difference between the molecular structures of CN01 and PBTZ169 in crystal are analyzed. CN01 and PBTZ169 show completely different conformations of the piperazine ring. Density functional theory analysis (DFT) and molecular dynamics (MD) simulation are performed to provide more details to explain the different antitubercular activity. All the analysis based on crystallography, quantum chemistry, and molecular modeling lay a foundation for the subsequent structural optimization of 8-CN benzothiazinones.

If you are hungry for even more, make sure to check my other article about 5308-25-8, Safety of 1-Ethylpiperazine.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics