Category: piperazines

109-01-3, Name is 1-Methylpiperazine, molecular formula is C5H12N2, belongs to piperazines compound, is a common compound. In a patnet, author is Jackl, Moritz K., once mentioned the new application about 109-01-3, COA of Formula: C5H12N2.

Spirocyclic Nitroxide Biradicals: Synthesis and Evaluation as Dynamic Nuclear Polarizing Agents

A method for the synthesis of rigid nitroxide biradicals with various spatial orientations between the radical centers is reported. Diketones were employed as substrates for tin amine protocol (SnAP) reagents to provide the parent spirocyclic diamines. Oxidation by peroxyacids provided the corresponding nitroxide biradicals. A set of four different biradicals with various interelectron distances and torsion angles between the radical planes was synthesized using this method. The exact geometries were determined by X-ray crystallography and the biradicals were investigated by EPR spectroscopy and evaluated for their dynamic nuclear polarization (DNP) performance. H-1-DNP enhancements in the range of 1.2-2.1 at 14.1 Tesla (600 MHz spectrometer) were achieved. This synthetic methodology opens a promising alternative to access nitroxide biradicals with various torsional angles and inter radical distances.

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is an experimental science, Name: 1-(4-Bromophenyl)-4-methylpiperazine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 130307-08-3, Name is 1-(4-Bromophenyl)-4-methylpiperazine, molecular formula is C11H15BrN2, belongs to piperazines compound. In a document, author is Hu, Ping.

Application of diazonium-induced anchoring process on ultrafiltration substrate for the fabrication of nanofiltration membrane with enhanced desalination performance

In membrane process, the lateral transport path of water molecule through substrate has a great impact on the permeance of thin-film composite (TFC) membrane, thus the optimization of substrate by constructing interlayer without affecting its pore structure is desired. Here, we report a facile, scalable and universal surface grafting strategy based on a diazonium-induced anchoring process (DIAP), for which an ultra-thin polyaminophenylene (PAP)-like layer is covalently grafted on the substrate. The PAP-like layer significantly increases the wettability of surface and pore as well as surface positive charges of substrate, but has little infiuence on its surface pore size and structure. Moreover, the effects of the anchored PAP-like layer on the distribution, release and uptake of piperazine (PIP) monomers during interfacial polymerization (IP) process are investigated systematically. The polyamide (PA) nanofiltration (NF) membrane made on this substrate features a highly cross-linked, thinner and smoother PA layer with less PA invasive, and highlights a 2-fold water fiux increase and simultaneously enhanced divalent salts (Na2SO4, MgSO4 and MgCl2) rejections (above 98.0%). Thus, combined with the superior structural stability and antifouling property, the obtained TFC membrane holds great potential in water soft ening and household water purification.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 130307-08-3. Name: 1-(4-Bromophenyl)-4-methylpiperazine.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is an experimental science, Application In Synthesis of (R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 300543-56-0, Name is (R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine, molecular formula is C17H19ClN2, belongs to piperazines compound. In a document, author is Li, Shao-Lu.

High-performance zwitterionic TFC polyamide nanofiltration membrane based on a novel triamine precursor

As known, piperazine (PIP) and m-phenylenediamine (MPD) are popularly employed as aqueous monomer to interfacially polymerize with trimesoyl chloride (TMC) for the fabrication of TFC polyamide NF and RO membrane, respectively. In this work, we designed a novel amine monomer 4-(piperazin-1-yl)benzene-1,3-diamine (PMPD) having the combined PIP and MPD units in one molecule and employing it with TMC to prepare the pristine nanofiltration membrane. Subsequently, zwitterionic antifouling PA surface was constructed by modification with 3-bromopropionic acid (3-BPA). The resulting membrane (PMPD-PA) exhibited a smoother surface with enhanced surface hydrophilicity than the membrane made from MPD, and the thickness of the PA active layer was down to similar to 35 nm. Meanwhile, its pure water permeability was-19 L m(-2) h(-1) bar(-1), with Na2SO4 rejection of 98.4%, and NaCl rejection as low as 24.1%, performing as a novel selective NF membrane. Furthermore, fouling tests using model foulants BSA and SA well illustrated the good antifouling properties of membrane PMPD-PA with the mitigated flux decline and enhanced flux recovery upon physical cleaning. Thus, this work further demonstrates the fabrication of high-performance TFC NF membrane from the perspective of molecular design.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 300543-56-0, in my other articles. Application In Synthesis of (R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: piperazines, 109-01-3, Name is 1-Methylpiperazine, molecular formula is C5H12N2, belongs to piperazines compound. In a document, author is Chen, Zhibiao, introduce the new discover.

An Efficient Solid-Liquid Biphasic Solvent for CO2 Capture: Crystalline Powder Product and Low Heat Duty

A nonaqueous, phase-change absorbent of 2-amino-2-methyl-1-propanol (AMP)/piperazine (PZ) and environmentally friendly solvent dipropylene glycol dimethyl ether (DME) fixes a number of issues suffered by a solid-liquid biphasic solvent, such as high viscosity of the saturated solution and difficult separation and regeneration of the viscous solid. The solid phase occupies 43% of the total volume while attributes about 94% of the total loading (0.87 mol mol(-1)) of the solution. Beside the formation of AMP-carbamate and PZ-carbamate according to zwitterions mechanism, the coupling products of AMP/PZ-carbamate are also found in the crystal, which helps to reduce the desorption temperature during the regeneration. Because of low solubility, self-aggregation, and high lattice energy in DME, the CO2 products precipitate and form a white crystalline powder in the lower phase of the solution. Meanwhile, the solid precipitation helps the bulk solution to keep a lower partial pressure and higher diffusivity of CO2, conforming a perfect performance of CO2 capture into the biphasic solvent. The regeneration heat duty of the solvent (1.61 GJ t(-1) CO2) was approximately 57% less than that of the benchmark monoethanolamine (MEA) because of its perfect performance on CO2 capture, such as high absorption loading, high regeneration efficiency, and low amount of rich phase required for regeneration. The novel absorbent has a great potential for green and sustainable CO2 capture.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 109-01-3. Category: piperazines.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 5625-37-6, Name is 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid, molecular formula is C8H18N2O6S2. In an article, author is Chouichit, Pakwilai,once mentioned of 5625-37-6, Safety of 2,2′-(Piperazine-1,4-diyl)diethanesulfonic acid.

A highly sensitive biosensor with a single-copy evolved sensing cassette for chlorpyrifos pesticide detection

A formylglycine-generating enzyme (FGE)-sulfatase-based whole cell biosensor was genetically improved into a single copy system by integrating the Sinorhizobium meliloti transcriptional activator ChpR and the chpA promoter-FGE-sulfatase fusion into the Escherichia coli chromosome. The sensitivity was further enhanced through a random mutagenesis of the chpR. The new integrated biosensor offered both a lower detection limit [5 nM chlorpyrifos (CPF)] and fluorescence background. The ready to use kit was developed using silica gel for on field detection. The biosensor kit was stable for 20 days when stored at 4 degrees C. Moreover, a 1-(1 naphthylmethyl)piperazine (NMP) efflux pump inhibitor can improve the sensitivity by 57%.

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

In an article, author is Liu, Caini, once mentioned the application of 147081-29-6, Formula: C10H20N2O2, Name is (S)-tert-Butyl 3-methylpiperazine-1-carboxylate, molecular formula is C10H20N2O2, molecular weight is 200.278, MDL number is MFCD02683204, category is piperazines. Now introduce a scientific discovery about this category.

High-performance nanofiltration membrane with structurally controlled PES substrate containing electrically aligned CNTs

A structurally controlled polyethersulfone (PES) membrane, as the substrate of the thin film composite nanofiltration (NF) membranes, was designed and fabricated with aligned carbon nanotubes (ACNTs) by a direct current electric field. The morphology and properties of the NF membranes were simultaneously affected by the PES substrate with especial macrovoids and ACNTs, increasing the permeability from 6.4 to 29.7 L/m(2) h bar. It was confirmed by FT-IR and XPS that the poly(piperazine amide) selective layer of the modified NF membrane has an increased content of -COOH for enhanced hydrophilicity. The zeta potential proves that the surface of the NF membrane modified by electric field has weaker negative charge than that of unmodified membrane in the range of pH = 5-9. Under the combined action of the Donnan effect and size exclusion, the rejection of MgCl2 increased while maintaining the dianion rejection above 95%. Particularly, the NF membrane modified with ACNTs exhibited better chlorine resistance and antifouling ability, thus improving the stability and perdurability of membranes. Our work utilizes the characteristics of ACNTs to explore its potential in NF membranes.

If you are interested in 147081-29-6, you can contact me at any time and look forward to more communication. Formula: C10H20N2O2.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

In an article, author is Liu, Meihong, once mentioned the application of 5294-61-1, HPLC of Formula: C14H21N3O, Name is N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide, molecular formula is C14H21N3O, molecular weight is 247.34, MDL number is MFCD06384973, category is piperazines. Now introduce a scientific discovery about this category.

Carbodiimide-assisted zwitterionic modification of poly(piperazine amide) thin-film composite membrane for enhanced separation and anti-depositing performances to cationic/anionic dye aqueous solutions

In this work, a novel method of carbodiimide-assisted zwitterionic modification was proposed and implemented to incorporate zwitterionic moieties onto poly(piperazine amide) membrane for improved water permeability and anti-depositing property, which are crucial for highly efficient nanofiltration of dye-contained effluents. Carboxyl groups of polyamide layer were firstly transferred into N-acylurea using excess l-ethyl-3-(3-(dimethylamino)propyl)-carbodiimide. Zwitterions were then incorporated through ring-opening reaction between tertiary amine groups of N-acylurea and 1, 4-butanesultone. Carbodiimide-assisted zwitterionic modification was verified by ATR-IR and XPS analyses and was found to not affect membrane pore size but significantly enhance membrane’s permeation and antidye-deposition performances. Compared with those of virgin membrane, water permeabilities of the desired zwitterionic membrane to pure water, Congo red aqueous solution and Victoria blue B aqueous solution were higher by 42.9, 62.3 and 95.2 %, respectively, hydraulic resistances from irreversible deposition of Congo red and Victoria blue B molecules were dramatically lowered by 68.4 and 91.8 %, respectively. Furthermore, the perm-selectivity performance of the desired zwitterionic membrane in terms of molecular weight cut-off and pure water permeability was better than most of the reported zwitterionic membranes, and the separation and anti-depositing performances to both anionic and cationic dye aqueous solutions were better than commercial membrane NF270.

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

Reference of 841-77-0, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 841-77-0, Name is 1-Benzhydrylpiperazine, SMILES is N1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCNCC1, belongs to piperazines compound. In a article, author is Rezaei, Mohammad Taher, introduce new discover of the category.

Synthesis of a tertiary amine by direct reductive amination of a carbonyl compound to form a scorpionate ligand; formation of Mn (II), Zn (II) and Cd (II) complexes, DFT calculations and, molecular docking studies

A hexadentate, asymmetric tripodal scorpionate type ligand, [[N1-Pyridin-2-ylmethyl-N1-[2-(4-pyridine2-ylmethyl-piperazine-1-yl)-ethyl]-ethane-1,2-diamine]] (L) has been prepared. To form this ligand, the direct reductive amination of a carbonyl compound by NaBH4 was used for the synthesis of tertiary amine. The complexes [MnL])ClO4((2), [CdL])ClO4((2), [ZnL])ClO4((2) have also been prepared. The synthesized compounds were characterized by elemental analyses, FT-IR, ESI-MS and, NMR spectroscopy. An X-ray crystal structure of [MnL] (ClO4)(2), shows that the coordination environment around the manganese is a distorted trigonal prism. The nature of metal-ligand bonding in the complexes was investigated by Natural Bond Orbital analysis, Energy Decomposition Analysis and Energy Decomposition Analysis using Natural Orbitals for Chemical Valence variation. Molecular docking has been used for the biological evaluation of the anticancer and antioxidant activities of the synthesized compounds. The docking results indicated that the Cd, Mn, and Zn-complexes had the highest binding affinity (MolDock Score) for the binding sites of cytochrome P450, myeloperoxidase, and cytochrome P450, respectively. (C) 2020 Elsevier B.V. All rights reserved.

Reference of 841-77-0, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 841-77-0 is helpful to your research.

Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 841-77-0, Name is 1-Benzhydrylpiperazine, formurla is C17H20N2. In a document, author is Faroughi Niya, Homayoun, introducing its new discovery. HPLC of Formula: C17H20N2.

Fe3O4@THAM-piperazine: a novel and highly reusable nanocatalyst for one-pot synthesis of 1,8-dioxo-octahydro-xanthenes and benzopyrans

A novel magnetically heterogeneous nanocatalyst has been successfully synthesized via the immobilization of piperazine on tris (hydroxymethyl) aminomethane-coated Fe3O4 magnetic nanoparticles. The described catalyst was fully characterized by various techniques such as FT-IR, EDS, DTG/TGA, XRD, TEM, SEM, and VSM analyses. The catalytic efficacy of Fe3O4@THAM-piperazine has investigated for one-pot synthesis of tetrahydrobenzo[b]pyran and 1,8-dioxo-octahydro-xanthene derivatives. Notable features of this user-friendly catalytic system include high yields, high catalytic activity, simple operation, non-toxicity, and easy work-up. Also, the new nanocatalyst could be easily recovered and reused for six times without significant loss of activity. [GRAPHICS]

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics

106261-49-8, Name is 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride, molecular formula is C13H20Cl2N2O2, belongs to piperazines compound, is a common compound. In a patnet, author is Bergman, Daniel A., once mentioned the new application about 106261-49-8, COA of Formula: C13H20Cl2N2O2.

Serotonergic-linked alterations of aggression of the crayfish

Current theory suggests that aggressive behavior in the crayfish is largely modulated and regulated by the neurotransmitter serotonin (5-HT). To test this theory that links serotonin to aggression, we performed a series of drug treatments using various serotonin-related chemicals to measure their effects on subsequent aggressive behavior. Treatments included serotonin, the serotonin precursor tryptophan, agonists: 1-(3-chlorophenyl) piperazine (m-CPP) and 5-Carboxy, an antagonist: cinanserin, and a serotonin receptor specific neurotoxin: 5,7-dihydroxytryptamine creatinine sulfate (5,7-DHT). Significant increases in aggression ofFaxonius rusticuscrayfish were observed when injected with serotonin and both agonists, however no decrease in aggression occurred with the antagonist. Crayfish injected with the agonist m-CPP increased aggression but did not directly confer success in fights. Our data support the current literature that the internal aggressive state of crayfish is altered by serotonin and its agonist/antagonists, however it does not on its own improve the aggressive fighting response and/or dominance status.

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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics