769944-39-0, tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution OF 4- (TERT-BUTOXYCARBONYL)-3- (4-CHLOROPHENYL) piperazine (330 mg, 1.1 mmol), 2-chloro-3-methyl-6-(4-pyridyl)pyrimidin-4-one (246 mg, 1.1 mmol) and triethylamine (170 mul, 1.22 mmol) in tetrahydrofuran were refluxed. Usual workup and purification by silica gel column chromatography gave 2- (L- (TERT-BUTOXY- CARBONYL)-2- (4-CHLOROPHENYL)-PIPERAZINE-4-YL)-3-METHYL-6- (4-PYRIDYL) pyrimidin- 4-one (500 mg, 93%). IH-NMR (CDC13) 5 : 1. 45 (9H, S), 3. 09 (1H, M), 3, 35 (3H, s), 3. 40-3. 63 (4H, M), 3. 96-4. 19 (2H, m), 5. 43 (1H, s), 6. 68 (1H, S), 7. 23 (2H, d, J=8. 3 HZ), 7. 32 (2H, d, J=8. 3 HZ), 7. 78 (2H, d, J=5. 9 HZ), 8. 72 (2H, d, J=5. 9 HZ)., 769944-39-0
769944-39-0 tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate 44558599, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; MITSUBISHI PHARMA CORPORATION; SANOFI-SYNTHELABO; WO2004/85408; (2004); A1;,
Piperazine – Wikipedia
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