Category: 2815-34-1piperazines

2815-34-1, trans-2,5-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

An NMP solution of fluoro-4-nitrobenzene and (+/-)-trans-2,5-dimethylpiperazine was stirred at an oil bath temperature of 120C for 3 hours to obtain (+/-)-trans-2,5-dimethyl-1-(4-nitrophenyl)piperazine, which was further treated in a similar manner to Example 4 to obtain an objective compound., 2815-34-1

As the paragraph descriping shows that 2815-34-1 is playing an increasingly important role.

Reference£º
Patent; YAMANOUCHI PHARMACEUTICAL CO. LTD.; EP1396487; (2004); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics

2815-34-1, trans-2,5-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Method 28 (25)-2, 5-Dimethyl-1- (‘4-nitrophenyDpiperazine; 1-Fluoro-4-nitrobenzene (6g, 42. 52mmol) and (2R, 5S)-2, 5-dimethylpiperazine (21.9g, 191. 34mmol) were heated in acetonitrile (20ml) at 100C for 1 lh. The solution was concentrated in vacuo, then the residue was partitioned between DCM and water + sat. sodium hydrogen carbonate. The organic extract was washed with water (4 times), brine, dried and concentrated. Chromatography on silica gel with MeOH : DCM (1: 99 to 5: 95) gave the title compound as an oil which solidified on standing overnight (8.32g, 83%). NMR (400 MHz) 1.08 (d, 3H), 1.16 (d, 3H), 2.55 (dd, 1H), 3. 18 (m, 2H), 3.34 (m, 2H), 3.95 (m, 1H), 6.91 (d, 2H), 8.03 (d, 2H); m/z 236.

2815-34-1, The synthetic route of 2815-34-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2005/75461; (2005); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics