Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers was written by Silva, Luiz R. G.;Rodrigues, Jose G. A.;de L. S. Vasconcellos, Maria;Ribeiro, Emerson S.;D’Elia, Eliane;de Q. Ferreira, Rafael. And the article was included in Ionics in 2022.Name: 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid The following contents are mentioned in the article:
The increasing presence of drugs in the environment has caused great concern in recent years due to their adverse side effects, whether related to animals or humans. In this aspect, the search for methods capable of controlling and monitoring these emerging contaminants in a simple, fast, low-cost, and environmentally friendly way becomes a very important research area that can assist in the preservation of the environment and human health. Therefore, the present work aims to propose for the first time the simultaneous electroanal. quantification of two drugs, extremely consumed worldwide (dipyrone and norfloxacin) of different classes (analgesic and antibiotic), in environmental and biol. samples (organic fertilizer, water, and urine). For this, a com. disposable boron-doped diamond electrochem. sensor (screen-printed electrodes) was used, in conjunction with portable equipment. A simple procedure was fully optimized for the determination of these two analytes by square wave voltammetry (SWV), including the choice of the best working pH and operational parameters of the technique. The SWV operational parameters were optimized using unified multivariate optimization for the best anal. condition for both drugs. The proposed method presents limit of detection of 0.30 and 0.40μmol L-1 for dipyrone and norfloxacin, resp. The anal. of the samples showed a recovery ranging from 94.0 to 105.0%, demonstrating that the method is suitable for performing the simultaneous determination in a few seconds, with no need for sample pre-treatment steps, and in a sustainable way. This study involved multiple reactions and reactants, such as 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (cas: 70458-96-7Name: 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid).
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (cas: 70458-96-7) belongs to piperazine derivatives. A form in which piperazine is commonly available industrially is as the hexahydrate, C4H10N2. 6H2O, which melts at 44 °C and boils at 125–130 °C. Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.Name: 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics