Sweeney, Joseph B. published the artcileA Simple, Broad-Scope Nickel(0) Precatalyst System for the Direct Amination of Allyl Alcohols, SDS of cas: 87179-40-6, the publication is Angewandte Chemie, International Edition (2018), 57(32), 10202-10206, database is CAplus and MEDLINE.
The first broad-scope nickel-catalyzed direct amination of allyl alcs., using an inexpensive NiII/Zn couple enabling the allylation of primary, secondary, and electron-deficient amines without the need for glove-box techniques, was reported. Under mild conditions, primary and secondary aliphatic amines reacted smoothly with a range of allyl alcs., giving secondary and tertiary amines efficiently. This “totally catalytic” method was also applied to electron-deficient nitrogen nucleophiles and the practicality of the process was demonstrated in an efficient, gram-scale preparation of the calcium antagonist drug substance flunarizine (Sibelium).
Angewandte Chemie, International Edition published new progress about 87179-40-6. 87179-40-6 belongs to piperazines, auxiliary class Benzenes, name is (E)-1-Cinnamylpiperazine, and the molecular formula is C6H13BO3, SDS of cas: 87179-40-6.
Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics