Continuously updated synthesis method about 54903-09-2

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Application of 54903-09-2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 6-Acetylbenzo[d]oxazol-2(3H)-one, is researched, Molecular C9H7NO3, CAS is 54903-09-2, about 6-Acyl benzoxazolinones. I. Author is Bonte, Jean P.; Lesieur, Daniel; Lespagnol, Charles; Plat, M.; Cazin, Jean C.; Cazin, Micheline.

6-Acylbenzoxazolinones I (R = H, Me, R1 = Me, CH2Cl, Et, Ph, CH2Ph, 2-thienyl) were prepared in 25-75% yield by treating 2-benzoxazolinone or 1-methyl-2-benzoxazolinone with R1CO2H and polyphosphoric acid. I (R = H, Me, R1 = CHO) was similarly prepared with hexamethylenetetramine and polyphosphoric acid. I had analgesic activity comparable to that of benzoxazolinone and aspirin, but lower antiinflammatory activity.

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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics