Formula: C5H10O3. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about A kinetic study and application of a novel carbonyl reductase isolated from Rhodococcus erythropolis. Author is Zelinski, Thomas; Kula, Maria-Regina.
The newly described carbonyl reductase from Rhodococcus erythropolis (RECR) accepts a broad range of substrates. Based on the kinetic constants of a variety of Me and Et ketones a hypothetical model of the substrate-binding site is proposed. Whether a substrate of interest may be reduced by the RECR can be predicted from this model together with the kinetic data. A study of initial velocities and product inhibition is presented, which shows that the kinetics of the RECR follow a Theorell-Chance mechanism. The pro-R hydride of NADH is transferred by the enzyme to the re face of the carbonyl compounds yielding (S)-alcs. The reduction of Me 3-oxobutanoate and Et 4-chloro-3-oxobutanoate catalyzed by the oxidoreductase lead to the corresponding hydroxy compounds with high enantiomeric purity [enantiomeric excess (e.e.) ≥99%]. The synthesis of Et (2R,3S)-3-hydroxy-2-methylbutanoate was accomplished with high diastereoselectivity (diastereomeric excess = 95%) and enantioselectivity (e.e. ≥95%).
Compound(53562-86-0)Formula: C5H10O3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-Methyl 3-hydroxybutanoate), if you are interested, you can check out my other related articles.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics