In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogs, published in 2021, which mentions a compound: 16004-15-2, Name is 1-(Bromomethyl)-4-iodobenzene, Molecular C7H6BrI, Reference of 1-(Bromomethyl)-4-iodobenzene.
Tyrosine sulfation is an important post-translational modification of peptides and proteins which underpins and modulates many protein-protein interactions. In order to overcome the inherent instability of the native modification, we report the synthesis of two sulfonate analogs and their incorporation into two thrombin-inhibiting sulfopeptides. The effective mimicry of these sulfonate analogs for native sulfotyrosine was validated in the context of their thrombin inhibitory activity and binding mode, as determined by X-ray crystallog.
There is still a lot of research devoted to this compound(SMILES：IC1=CC=C(CBr)C=C1)Reference of 1-(Bromomethyl)-4-iodobenzene, and with the development of science, more effects of this compound(16004-15-2) can be discovered.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics