Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 16004-15-2, is researched, SMILESS is IC1=CC=C(CBr)C=C1, Molecular C7H6BrIJournal, Article, Angewandte Chemie, International Edition called Palladium-Catalyzed Electrophilic Functionalization of Pyridine Derivatives through Phosphonium Salts, Author is Che, Yuan-Yuan; Yue, Yanni; Lin, Ling-Zhi; Pei, Bingbing; Deng, Xuezu; Feng, Chao, the main research direction is heterobiaryl pyridine preparation electrophilic coupling phosphonium pyridine iodoarene; cross-coupling; palladium; phosphonium salts; pyridines; silver.Name: 1-(Bromomethyl)-4-iodobenzene.
Herein, we report a highly efficient and practical method for pyridine-derived heterobiaryl synthesis through palladium-catalyzed electrophilic functionalization of easily available pyridine-derived quaternary phosphonium salts. The nice generality of this reaction was goes beyond arylation, enabling facile incorporation of diverse carbon-based fragments, including alkenyl, alkynyl, and also allyl fragments, onto the pyridine core. Notably, the silver salt additive is revealed to be of vital importance for the success of this transformation and its pivotal role as transmetallation mediator, which guarantees a smooth transfer of pyridyl group to palladium intermediate, is also described.
Here is a brief introduction to this compound(16004-15-2)Name: 1-(Bromomethyl)-4-iodobenzene, if you want to know about other compounds related to this compound(16004-15-2), you can read my other articles.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics