115619-01-7, 4-(4-Ethylpiperazin-1-yl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(5-Chlorothieno[2,3-c]pyridin-2-yl)(2,6-difluoro-3,5-dimethoxyphenyl)methanol (730 mg, 1.96 mmol), 4 -(4-ethylpiperazin-1-yl)aniline (590 mg, 2.36 mmol), Pd2 (dba) 3 (360 mg, 0.393 mmol), XantpHos (454 mg, 0·785 mmol), Cs2CO3 (1.28 g, 3.93 mmol) It was mixed with toluene (10 ml) and stirred at 110 C under Ar protection overnight. The reaction solution was directly dried by column chromatography (dichloromethane:methanol = 95:5) to give compound (2,6-difluoro-3,5-dimethoxyphenyl) (5-((4-(4-) Ethyl piperazin-1-yl)phenyl)amino)thieno[2,3-c]pyridine-2-yl)methanone 1 g, purity 80%, yield 86.8%.
115619-01-7, The synthetic route of 115619-01-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Shanghai Xin Qibo Biological Technology Co., Ltd.; Wang Zhaoyin; Ma Jianbin; (39 pag.)CN110092798; (2019); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics