76003-29-7, 1-Boc-3-Oxopiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,76003-29-7
To a solution of 50.0 mmol of 5 and 60.0 mmol of 7 in 50.0 mL of 1,4-dioxane was added 0.500 mmol of copper (I) iodide followed by the addition of 100 mmol of K3P04 and 5 mmol of trans-cyclohexanediamine, then the resulting mixture was stirred at 100C for 16 h. The reaction mixture was cooled to rt and diluted with 500 mL of H20. The resulting aqueous solution was extracted with CHC13. The organic phase was washed with saturated NaCl, dried over MgS04 and concentrated in vacuo. The crude product was purified by column chromatography to give 43.4 mmol of 8. 4.2 Results [0176] Analytical data for exemplary compounds of structure 8 are provided below. 4.2.a tert-Butvl 4-(6-aminop_vridin-3-vl)-3-oxopiperazine-I -carboxvlate [0177] ‘H NMR (400 MHz, CDC13) No. 7.97-8.00 (m, 1H), 7.35-7.40 (m, 1H), 6.50-6.54 (m, 1H), 4.54 (br s, 2H), 4.24 (s, 2H), 3.65-3.69 (m, 2H), 3.75-3.80 (m, 2H), 1.50 (s, 9H); MS m/z: 293 (M+1).
As the paragraph descriping shows that 76003-29-7 is playing an increasingly important role.
Reference：
Patent; ICAGEN, INC.; ASTELLAS PHARMA INC.; WO2005/99711; (2005); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics