103-76-4, N-(2-Hydroxyethyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of hydroxyethyl piperazine (13 ml) in acetone (200 ml), a 10% solution of sodium hydrogencarbonate (254 ml) was added under vigorous stirring. Subsequently, the reaction mixture was cooled to 0 C. and benzyl chloroformate (17.92 ml) was added in drops. The reaction mixture was stirred for 4 hours at room temperature. After removing the acetone under vacuum, the aqueous phase was extracted with acetic acid ethyl ester (3¡Á250 ml). The combined organic phases were washed once with a saturated solution of sodium chloride, dried over sodium sulfate, filtered, concentrated and resulted in the desired product (28.2 g).MS (EI): m/z: 265 [M+H]+
103-76-4, 103-76-4 N-(2-Hydroxyethyl)piperazine 7677, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; Morphochem Aktiengesellschaft Fur Kombinatorische Chemie; US2010/324030; (2010); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics