With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.859518-35-7,tert-Butyl 3-cyanopiperazine-1-carboxylate,as a common compound, the synthetic route is as follows.,859518-35-7
To a mixture of tert-butyl 3 -cyanopiperazine- 1 -carboxylate (200 mg, 0.95 mmol) in dichioromethane (10 mL), CF3COOH (2 mL) was added and theresulting was stirred at RT for 1 h. The mixture was concentrated in vacuo to afford the crude product.
859518-35-7 tert-Butyl 3-cyanopiperazine-1-carboxylate 53487922, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; ARAXES PHARMA LLC; JANES, Matthew, Robert; PATRICELLI, Matthew, Peter; LI, Liansheng; REN, Pingda; LIU, Yi; (397 pag.)WO2016/44772; (2016); A1;,
Piperazine – Wikipedia
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