Analyzing the synthesis route of 5625-67-2

5625-67-2, As the paragraph descriping shows that 5625-67-2 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5625-67-2,Piperazin-2-one,as a common compound, the synthetic route is as follows.

Piperazine-2-one (1 g, 10 mmol) is added to ethyl acetate (40 mL),In the solution of 20 ml ,K2CO3 is added at the room temperature followed by Benzyloxycarbonyl chloride (2.1 mL, 15 mmol) is added dropwise to the reaction flask,and reaction is stirred at room temperature . The reaction stopped next day, and the organic layer is washed with 20 mL of X saturated NaCl solution, dried over anhydrous magnesium sulfate,Column chromatography (D: Mu = 75: 1) to obtain a white solid 1.48, 59.8%.yield.

5625-67-2, As the paragraph descriping shows that 5625-67-2 is playing an increasingly important role.

Reference：
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Xu Boling; Chen Xiaoguang; Zhou Jie; Ji Ming; Yao Haiping; Zhou Qin; (57 pag.)CN107098886; (2017); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics