30459-17-7, 1-(4-Trifluoromethylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,30459-17-7
General procedure: A solution of arylpiperazine (5.5 mmol) and triethylamine (0.8 mL;5.5 mmol) in anhydrous THF (20 mL) was added dropwise to a stirredsolution of an appropriate alkyl [2-/3-(bromoacetyl)phenyl]carbamate(5.5 mmol) in anhydrous THF (30 mL), and the mixture stirred for 3 h atambient temperature. The solvents were removed under reduced pressure,and added chloroform (100 mL) and water. The organic phase waswashed with additional water, dried over anhydrous sodium sulfate andthe solvent removed under reduced pressure, to give a solid crudeproduct, which was recrystallized from acetone.
The synthetic route of 30459-17-7 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Campos, Ludmila E.; Garibotto, Francisco M.; Angelina, Emilio; Kos, Jiri; Toma?i?, Tihomir; Zidar, Nace; Kikelj, Danijel; Gonec; Marvanova, Pavlina; Mokry, Petr; Jampilek; Alvarez, Sergio E.; Enriz, Ricardo D.; Bioorganic Chemistry; vol. 91; (2019);,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics