Some tips on 169447-70-5

The synthetic route of 169447-70-5 has been constantly updated, and we look forward to future research findings.

169447-70-5, (S)-tert-Butyl 2-methylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of (S)-tert-butyl 2-methylpiperazine-1- carboxylate (1.42 g, 7.09 mmol), 1-fluoro-4-nitrobenzene(1 g, 7.09 mmol) and potassium carbonate (1.47 g, 10.6 mmol) in DMF (6 mL) was heated at 50 C for 20 h. The reaction mixture was cooled to room temperature and diluted with water (50 mL) . The resulting precipitate was collected by filtration and washed with water to give thetitle compound (1.83 g, 80%) . LCMS (Method A) : = 1.45 mi m/z = 266 [M+H-tBu]., 169447-70-5

The synthetic route of 169447-70-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ALMAC DISCOVERY LIMITED; HARRISON, Timothy; TREVITT, Graham; HEWITT, Peter Robin; O’DOWD, Colin Roderick; BURKAMP, Frank; WILKINSON, Andrew John; SHEPHERD, Steven D.; MIEL, Hugues; WO2015/92431; (2015); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics