Brief introduction of 24860-46-6

24860-46-6 2-(2-Oxopiperazin-1-yl)acetic acid 23422809, apiperazines compound, is more and more widely used in various fields.

24860-46-6, 2-(2-Oxopiperazin-1-yl)acetic acid is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Palladium (0.161 g, 10% on carbon) was added to a mixture of 2-Oxo-1-piperazineacetic acid (0.497 g, 3.14 mmol) and (2-Oxo-ethyl)-carbamic acid tert-butyl ester (0.503 g, 3.16 mmol) in methanol (6.2 mL) under argon. The flask was evacuated and the reaction placed under a hydrogen atmosphere for 22 h. The reaction was filtered through a Celite -plugged filter frit, washed with methanol and DCM, and concentrated in vacuo to afford crude product which was carried to the next step without purification. ESI-MS m/z 324 (M+Na)+., 24860-46-6

24860-46-6 2-(2-Oxopiperazin-1-yl)acetic acid 23422809, apiperazines compound, is more and more widely used in various fields.

Reference:
Patent; VENATORX PHARMACEUTICALS, INC.; BURNS, Christopher, J.; DAIGLE, Denis; LIU, Bin; MCGARRY, Daniel; PEVEAR, Daniel, C.; TROUT, Robert, E. Lee; WO2014/151958; (2014); A1;,
Piperazine – Wikipedia
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