Analyzing the synthesis route of 31166-44-6

The synthetic route of 31166-44-6 has been constantly updated, and we look forward to future research findings.

31166-44-6, 1-Cbz-Piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

31166-44-6, Benzyl Piperazine-1-carboxylate (10.50 g)In tetrahydrofuran (225 mL) were added triethylamine (5.51 g), sodium iodide (0.68 g) and 3-bromo-1-propanol (9.77 g). It was then stirred at 50 ° C. overnight. Thereafter, it was cooled to room temperature. The resulting solution was poured into water and extracted with ethyl acetate. The organic layers were combined and washed with saturated brine to give the title compound (11.62 g, yield 92percent).

The synthetic route of 31166-44-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; NIPPON SODA COMPANY LIMITED; IHORI, YOICHI; INOUE, SHUJI; SHIBAYAMA, KOTARO; KANG, CHANG-KYUNG; SHIINOKI, YASUYUKI; NISHIMURA, SATOSHI; (65 pag.)JP2016/222654; (2016); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics