1589082-06-3, (S)-tert-Butyl 3-(cyanomethyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A reaction mixture of fert-butyl (3,51-3- (cyanomethyl)piperazine-l-carboxylate (850 mg, 3.77 mmol) and HCl/dioxane (4 M, 20 mL) was stirred at 15 C for 1 hour. Upon completion, the solvent was removed under vacuum to give 2-[(25)-piperazin-2-yl]acetonitrile (740 mg, 3.74 mmol, 99.0% yield, 2HC1) as a white solid. NMR (400MHz, METHANOLS) delta = 4.04 – 3.90 (m, 1H), 3.81 – 3.70 (m, 2H), 3.69 – 3.61 (m, 2H), 3.53 – 3.36 (m, 2H), 3.13 (d, J=6.4 Hz, 2H)., 1589082-06-3
As the paragraph descriping shows that 1589082-06-3 is playing an increasingly important role.
Reference£º
Patent; MIRATI THERAPEUTICS, INC.; ARRAY BIOPHARMA, INC.; FISCHER, John, P.; FELL, Jay, Bradford; BLAKE, James, F.; HINKLIN, Ronald, Jay; MEJIA, Macedonio, J.; HICKEN, Erik, James; CHICARELLI, Mark, Joseph; GAUDINO, John, J.; VIGERS, Guy, P.A.; BURGESS, Laurence, E.; MARX, Matthew, Arnold; CHRISTENSEN, James, Gail; LEE, Matthew, Randolf; SAVECHENKOV, Pavel; ZECCA, Henry, J.; (529 pag.)WO2017/201161; (2017); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics