889939-92-8, 2-(1-Methylpiperazin-2-yl)ethanol is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
889939-92-8, 974 mg of Nu,Nu-diisopropylethylamine and 724 mg of 2-(1 -methylpiperazin-2-yl)ethanol are added to a suspension of 1 g of 4-fluoro-1 -nitro-2-(propan-2-yloxy)benzene in 10 ml of acetonitrile. The reaction medium is microwave-heated at 1 10C for 6 hours and then concentrated to dryness under reduced pressure. Purification is carried out by flash chromatography on silica gel (40-63 microns), elution being carried out with a mixture of dichloromethane and methanol (100/0) to (90/10). 1 .15 g of 2-{1 -methyl-4-[4-nitro-3- (propan-2-yloxy)phenyl]piperazin-2-yl}ethanol are obtained in the form of a yellow oil.
The synthetic route of 889939-92-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stephanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice; WO2013/150036; (2013); A1;,
Piperazine – Wikipedia
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