Simple exploration of 148546-99-0

148546-99-0, 148546-99-0 3-(4-Methylpiperazin-1-yl)aniline 11564613, apiperazines compound, is more and more widely used in various fields.

148546-99-0, 3-(4-Methylpiperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of intermediate 6 (prepared according to A2. c-1) (0.0005 mol) and 3-(4-methyl-1-piperazinyl)-benzenamine (0.0005 mol) in 2-methoxyethanol (4 ml) was stirred for 1 hour at 100C and the solvent was evaporated. The residue was stirred in DIPE and then the DIPE was decanted off. The residue was dissolved in CH3OH, warmed and acidified with HCl/2-propanol. The resulting precipitate was filtered off and dried. Yield: 0.123 g of final compound 36 (51.5 %; M. p.: > 250C).

148546-99-0, 148546-99-0 3-(4-Methylpiperazin-1-yl)aniline 11564613, apiperazines compound, is more and more widely used in various fields.

Reference£º
Patent; JANSSEN PHARMACEUTICA N.V.; WO2005/12304; (2005); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics