109-01-3, 1-Methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 5 (Synthesis of 4-[(4-methyl-1-piperazinyl)methyl]benzoic acid 4-(Chloromethyl)benzoic acid (58 g) is added to a solution of N-methylpiperazine (150 g) in n-BuOH (580 g) at room temperature. After stirring for 3-6 h, the solvent is evaporated under reduced pressure and the residue is taken up with IPA (440 g). The mixture is refluxed for 15 min under stirring, then stirred for 24 h at room temperature. The solid is filtered off, washed with IPA (2*58 g) and dried under vacuum at 70 C. overnight. The desired product is obtained as a white solid (59.5 g, 75% yield).
109-01-3, As the paragraph descriping shows that 109-01-3 is playing an increasingly important role.
Reference£º
Patent; MacDonald, Peter; Rossetto, Pierluigi; US2008/103305; (2008); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics