59878-57-8,59878-57-8, 1-(Cyclopropylcarbonyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a microwave vial were added methyl 4-((3-methylen-4-oxo-1,2,3,4-tetrahydrocarbazol-9-yl)methyl)benzoate [formula 2-4] (0.10 g, 0.290 mmol), 1-(cyclopropylcarbonyl)piperazine (0.134 g, 0.869 mmol) and toluene (3.0 mL), and a reaction was carried out in a microwave reactor at 120 C. for 90 minutes. Then, the reaction mixture was extracted with ethyl acetate and saturated NH4Cl aqueous solution, the organic layer was washed with brine, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. Residue was purified by column chromatography (SiO2; dichloromethane/methanol, 10/1) to yield the title compound (0.056 g, 39%).
The synthetic route of 59878-57-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CHONG KUN DANG PHARMACEUTICAL CORP.; Kim, Yuntae; Lee, Changsik; Yang, Hyun-mo; Choi, Hojin; Min, Jaeki; Kim, Soyoung; Kim, Dal-Hyun; Ha, Nina; Kim, Jung-Min; Lim, Hyojin; Ko, Eunhee; US2014/315889; (2014); A1;,
Piperazine – Wikipedia
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