Analyzing the synthesis route of 5308-25-8

The synthetic route of 5308-25-8 has been constantly updated, and we look forward to future research findings.

5308-25-8, 1-Ethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

0.36 g of N- [4-tert-butyl-5- (4-methoxybenzylthiazolyl) -2-yl] -2-chloroacetamideAnd 5 mL of tetrahydrofuran were added and stirred at room temperature, 0.24 g of pyridine and 0.23 g were added N-ethylpiperazine; reaction overnight, desolvation, plus dichloromethane,Saturated with salt water, dried over anhydrous sodium sulfate,Plus petroleum ether precipitation solid, suction filter, petroleum ether wash,Dried to give a pale yellow solidN- [4-tert-butyl-5- (4-methoxybenzylthiazolyl) -2-yl]2- (N-ethylpiperazinyl) acetamide in a yield of 65.1%

The synthetic route of 5308-25-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Hunan University; Hu Aixi; Ding Na; Ye Jiao; (15 pag.)CN106938989; (2017); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics