122833-04-9, 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
[0105] To a solution of compound 7 (260 mg, 0.6 mmol) inbutan-2-ol (1 mL) were added 2-methoxy-4-( 4-methylpiperazin-1-yl)aniline (133 mg, 0.6 mmol) and trifluoroacetic acid( 48 flL, 0.6 mmol). The reaction mixture was heated to 110C. and reacted in a sealed tube for 24 h, diluted by DCM,washed by saturated NaHC03 solution, washed by saturatedbrine, dried by anhydrous Na2S04 , evaporated the solventunder reduced pressure, and then purified by colunm chromatographyto yield a yellow solid (151 mg, 44%).[0106] 1H NMR (400Hz, CDCI3 ) o 7.99 (s, lH), 7.48 (d,1=7.5 Hz, lH), 7.44 (s, lH), 7.41 (t, 1=8.0 Hz, lH), 7.35 (s,lH), 6.97 (d, 1=7.5 Hz, lH), 6.63 (s, lH), 6.42 (d, 1=2.0 Hz,lH), 6.16 (d, 1=6.4 Hz, lH), 4.42 (s, 2H), 3.80 (s, 3H), 3.22(m, 4H), 3.08 (s, 3H), 2.79 (m, 4H), 1.47 (s, 9H).[01 07]
122833-04-9, As the paragraph descriping shows that 122833-04-9 is playing an increasingly important role.
Reference£º
Patent; GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES; Ding, Ke; Chang, Shaohua; Xu, Shilin; Zhang, Lianwen; Tu, Zhengchao; Ding, Jian; Geng, Meiyu; Chen, Yi; US2014/296216; (2014); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics