New learning discoveries about (R)-1-Boc-2-Ethylpiperazine

As the paragraph descriping shows that 393781-70-9 is playing an increasingly important role.

393781-70-9, (R)-1-Boc-2-Ethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of (R)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester (1 g) and 3,5-dimethylpyridine-N-oxide (546 mg)in tetrahydrofuran (18 mL) were added N,N-diisopropylethylamine (3 mL) and bromotris(pyrrolidino)phosphonium hexafluorophosphate (2.8 g) and the mixture was stirred at room temperature overnight. Water was added to the reaction mixture,and the mixture was extracted with ethyl acetate and chloroform. The solvent was evaporated and the obtained residue was purified by column chromatography (ethyl acetate:hexane)to give (R)-4-(3,5-dimethylpyridin-2-yl)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester (1.11 g)., 393781-70-9

As the paragraph descriping shows that 393781-70-9 is playing an increasingly important role.

Reference£º
Patent; Mitsubishi Tanabe Pharma Corporation; ISHIBUCHI, Seigo; SARUTA, Kunio; HAMADA, Maiko; MATOBA, Nobuatsu; MATSUDAIRA, Tetsuji; SEKI, Maki; TARAO, Akiko; HONJO, Takashi; OGATA, Shingo; KAWATA, Atsushi; MOROKUMA, Kenji; FUJIE, Naoto; AOYAMA, Yukio; (251 pag.)EP3321256; (2018); A1;,
Piperazine – Wikipedia
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