103-76-4, N-(2-Hydroxyethyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of 1-(2-Hydroxyethyl)piperazine (8.0 g, 61.45 mmol, 1.0 eq) in 1,4-dioxane (80 ml) di-tert-butyldicarbonate (15.93 g, 73.7 mmol, 1.2eq) was added at 0C. The reaction mixture was allowed to stir at room temperature for 3 hours. TLC indicated starting material was consumed and the desired product was observed. The reaction mixture was evaporated under reduced pressure to get the desired compound (11.0 g, 77.7% yield) as light green color syrup solid. This was used directly for next step without further purification. 1H NMR (300 MHz, CDCl3): delta ppm 3.65-3.61 (m, 2H), 3.46-3.43 (m, 4H), 2.55 (t, J = 5.4 Hz, 2H), 2.47-2.44 (m, 4H), 1.45 (s, 9H); ES Mass: [M+Na]+253.09 (100%).
103-76-4, As the paragraph descriping shows that 103-76-4 is playing an increasingly important role.
Reference£º
Patent; HETERO RESEARCH FOUNDATION; PANDURANGA ADULLA, Reddy; PARTHASARADHI REDDY, Bandi; MANOHAR SHARMA, Vedula; RATHNAKAR REDDY, Kura; PREM KUMAR, Mamnoor; BHASKAR REDDY, Kasireddy; NARSINGAM, Mogili; VENKATI, Mukkera; VL SUBRAHMANYAM, Lanka; MALLIKARJUN REDDY, Ravi; WO2013/160810; (2013); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics