21655-48-1, cis-2,6-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate 66: (3R*,5Si:)-3,5-Dimethyl-piperazin-l-yl)-(l-m-tolyl-lH-[l ,2,4]triazol-3-yl)- methanone A mixture of 610 mg (3.00 mmol) l-m-tolyl-lH-[l,2,4]triazole-3-carboxylic acid, 350 mg (3.00 mmol) cz’s-2,6-dimethyl-piperazine, 1.06 g (3.30 mmol) TBTU and 770 mu, (4.50 mmol) DIPEA in 5.0 mL DMF was stirred with at RT for 12 h. The reaction mixture was poured into ice water and extracted with EtOAc. The combined organic phases were washed with saturated NaHC03 solution, dried over sodium sulfate, filtered and concentrated in vacuo. Yield: 520 mg (58 percent) ESI-MS: m/z = 300 (M+H)+ Rt(HPLC): 0.80 min (method 8), 21655-48-1
As the paragraph descriping shows that 21655-48-1 is playing an increasingly important role.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; HEIMANN, Annekatrin; DAHMANN, Georg; GRUNDL, Marc; MUELLER, Stephan Georg; WELLENZOHN, Bernd; WO2013/87805; (2013); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics