122833-04-9, 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
tert-butyl 4-(3-benzyl-7-(methylsulfonyl)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)piperidine-1-carboxylate (7) (1g, 2mmol) was added sec-butyl alcohol containing 10mL sealed vial, was added successively 2-methoxy-4-(4-methylpiperazin-1-yl)aniline ( 531mg, 2.4mmol) and TFA (180muL, 2.4mmol).It was heated to 110C, stirred for 18 hours. Cooled to room temperature, poured into 10% NaHCO3Aqueous solution, extracted with methylene chloride twice, combined organic phase was washed with water twice and saturated brine, dried over anhydrous Na2SO4Dried, filtered and spin dry, column chromatography solid 0.684g (53.3%).
122833-04-9, The synthetic route of 122833-04-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Guangzhou Institute of biomedicine and health, Chinese Academy of Sciences; Ding, Ke; Xu, Shilin; Xu, Tianfeng; Zhang, Lianwen; Ding, Fang; Tu, Zhengchao; Lu, Xiaoyun; Ding, Jian; Geng, MeiYu; (82 pag.)CN104418860; (2016); B;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics