1228780-72-0, 1-((4′-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Under nitrogen protection, Compound 20 (1.0 g, 3.13 mmol), Compound 1 (0.9 g, 3.13 mmol) and dipotassium hydrogen phosphate (1.10 g, 6.26 mmol) Add to a solution of dimethyl sulfoxide (DMSO, 25 ml), The reaction solution was reacted at 140 C for 12 h, and cooled to room temperature. The reaction was quenched with water (50 mL). Dry over anhydrous sodium sulfate, remove the solvent,The concentrate is subjected to column separation (eluent: petroleum ether/ethyl acetate (v/v) = 3:1), Obtained 1.4 g of a yellow oil, The yield was 76%.
1228780-72-0, As the paragraph descriping shows that 1228780-72-0 is playing an increasingly important role.
Reference£º
Patent; Shenzhen Tajirui Bio-pharmaceutical Co., Ltd.; Wang Yihan; Liu Zhiqiang; (35 pag.)CN108658983; (2018); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics