67455-41-8, 4-(Piperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,67455-41-8
General procedure: A mixture of compounds 5a-5i (10.0 mmol), concentrated hydrochloricacid (12.2 mmol) and melamine (20.0 mmol) in isopropylalcohol (10.0 mL) was refluxed for 8 h. Progress of reaction wasmonitored by tlc and after complete conversion of starting materialreaction mixture was cooled to rt. The reaction mixture wasquenched in saturated sodium carbonate solution (20.0 mL) andfiltered. The solid was washed with water (50.0 mL). The crudeproduct thus obtainedwas dried at 50 C under reduced pressure toget compounds 6a-6i.
The synthetic route of 67455-41-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Zhao, Hui; Hu, Xiaoxia; Cao, Kai; Zhang, Yue; Zhao, Kuantao; Tang, Chunlei; Feng, Bainian; European Journal of Medicinal Chemistry; vol. 157; (2018); p. 935 – 945;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics