5294-61-1, N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5294-61-1
To a solution of benzyl OXIRAN-2-YMETHYLCARBAMATE (12mmoles, 2. 5G) in ethanol (LOOML) was added triethylamine (24mmoles, 3. 34ML), followed by the addition of N- (2, 6- DIMETHYLPHENYL)-2-PIPERAZINYLACETAMIDE (24mmoles, 5.94g), a compound of formula (4). The resulting mixture was refluxed for 18 hours, then solvent removed from the reaction mixture under reduced pressure. The residue was purified by column chromatography on silica gel, eluting with 5% MEOH/DICHLOROMETHANE to give N-(2, 6-DIMETHYLPHENYL)-2-(4- {2-HYDROXY-3- [(PHENYLMETHOXY) carbonylamino] propyl} piperazinyl) acetamide, a compound of formula (5), as an off-white solid. Yield: 2.25g.
As the paragraph descriping shows that 5294-61-1 is playing an increasingly important role.
Reference£º
Patent; CV THERAPEUTICS, INC.; WO2004/63180; (2004); A1;,
Piperazine – Wikipedia
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