Perrone, Roberto et al. published their research in Medicinal Chemistry Research in 2000 | CAS: 21867-64-1

1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.Recommanded Product: 21867-64-1

N-aryl- or N-alkylpiperazine derivatives: the role of N-substituent on σ1, σ2, 5-HT1A and D2 receptor affinity was written by Perrone, Roberto;Berardi, Francesco;Colabufo, Nicola A.;Leopoldo, Marcello;Abate, Carmen;Tortorella, Vincenzo. And the article was included in Medicinal Chemistry Research in 2000.Recommanded Product: 21867-64-1 This article mentions the following:

The binding profile at σ1, σ2, 5-HT1A and D2 receptors of eight N-substituted-N’-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazines is reported. Results indicated that a suitable substitution can lead to potent 5-HT1A or σ1, or σ2 ligands. In the experiment, the researchers used many compounds, for example, 1-Propylpiperazine (cas: 21867-64-1Recommanded Product: 21867-64-1).

1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.Recommanded Product: 21867-64-1

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics