Niewiadomy, Andrzej published the artcileSynthesis and biological activity of novel N,n-cyclic-2,4-dihydroxythiobenzamide derivatives, Name: (E)-1-Cinnamylpiperazine, the publication is Acta Poloniae Pharmaceutica (2015), 72(5), 943-950, database is CAplus.
A series of novel N,N-cyclic-2,4-dihydroxythiobenzamide derivatives is described. Test compounds were formed by the reaction of the com. available reagents with sulfinylbis[(2,4- dihydroxyphenyl)methanethione] (STB). The chem. structures were confirmed by IR, 1H NMR, 13CNMR, EI-MS, and elemental anal. For the estimation of potential activity in vitro, the MIC values against strains of Candida were determined Antifungal properties of selected compounds under in vitro conditions against five phytopathogenic fungi were estimated Furthermore, the antiproliferative activity against the HCV29T cancer cell lines has been studied. These compounds exhibited antiproliferative activity in the range of 33.98 n 10.51 μg/mL.
Acta Poloniae Pharmaceutica published new progress about 87179-40-6. 87179-40-6 belongs to piperazines, auxiliary class Benzenes, name is (E)-1-Cinnamylpiperazine, and the molecular formula is C13H18N2, Name: (E)-1-Cinnamylpiperazine.
Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics