Dehydrated crystalline form of (3Z)-2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl) acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester ethanesulfonate was written by Anonymous. And the article was included in IP.com Journal in 2015.Application of 656247-18-6 The following contents are mentioned in the article:
Described herein after is a dehydrated form of the hemihydrate form of (3Z)-2,3-dihydro-3- [[[4-[methyl[2-(4-methyl-1-piperazinyl) acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H- indole-6-carboxylic acid Me ester ethansulfonate (referred to as Compound A). The water content of the dehydrated form is of about 0.32%, determined by Karl Fischer (KF) method, whereas the theor. value of water content for Compound A as a hemihydrate form is 1.37%. This study involved multiple reactions and reactants, such as (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate ethanesulfonate (cas: 656247-18-6Application of 656247-18-6).
(Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate ethanesulfonate (cas: 656247-18-6) belongs to piperazine derivatives. Piperazine causes primary dermal irritation and skin burns at high concentrations. Piperazine also causes eye irritation in humans. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.Application of 656247-18-6
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics