Sanjeevarayappa, C. published the artcileDesign, synthesis, characterization and biological evaluation of novel amides containing 1,2,4-oxadiazole derivatives, Product Details of C10H17N3O2, the publication is Journal of Applicable Chemistry (Lumami, India) (2014), 3(1), 38-46, 9 pp., database is CAplus.
Some new amides containing oxadiazole derivatives, I (R = 2,3-F2C6H3, 2,4-Cl2C6H3, c-C6H11, 1-methyl-2-indolyl, etc.), have been synthesized using N-Boc piperazine as starting material. The latter was converted to N-cyano-4-Boc piperazine by nucleophilic substitution reaction. The substituted product was treated with hydroxylamine hydrochloride under basic conditions to give the hydroxycarbamimide and was cyclized with 3-fluorobenzoic acid to yield N-protected piperazinyl-1,2,4-oxadiazole. Deprotection of the secondary amine was done using trifluoroacetic acid; the free amine was then condensed with different substituted acids, RCO2H, in the presence of triethylamine to yield the title compounds All the synthesized compounds were screened for their in vitro antibacterial activity and anthelmintic activity. Some of the compounds showed good biol. activity.
Journal of Applicable Chemistry (Lumami, India) published new progress about 113534-02-4. 113534-02-4 belongs to piperazines, auxiliary class Piperazine,Nitrile,Amide, name is tert-Butyl 4-cyanopiperazine-1-carboxylate, and the molecular formula is C10H17N3O2, Product Details of C10H17N3O2.
Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics