Keith, John M. published the artcileDual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore, Application In Synthesis of 71260-16-7, the publication is Bioorganic & Medicinal Chemistry Letters (2007), 17(3), 702-706, database is CAplus and MEDLINE.
A series of tetrahydroisoquinolines, e.g., I, acting as dual histamine H3/serotonin transporter ligands is described. A highly regio-selective synthesis of the tetrahydroisoquinoline core involving acid mediated ring-closure of an acetophenone intermediate followed by reduction with NaCNBH3 was developed. In vitro and in vivo data are discussed.
Bioorganic & Medicinal Chemistry Letters published new progress about 71260-16-7. 71260-16-7 belongs to piperazines, auxiliary class Piperazine, name is 2-Methyl-1-(piperazin-1-yl)propan-1-one, and the molecular formula is C8H16N2O, Application In Synthesis of 71260-16-7.
Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics