Rolston, K. V. I. published the artcileComparative in vitro activity of the new difluoro-quinolone temafloxacin (A-62254) against bacterial isolates from cancer patients, Related Products of piperazines, the main research area is temafloxacin sensitivity bacteria cancer patient.
The in vitro activity of temafloxacin, a new difluoro quinoline agent, against 725 bacterial isolates representing 32 species was evaluated in comparison with that of ciprofloxacin. Temafloxacin inhibited the majority of Enterobacteriaceae isolates at a concentration of ≤0.5 μg/mL. It was also extremely active against Acinetobacter spp. and Aeromonas hydrophila. Its activity was 2-8 fold less than that of ciprofloxacin against most gram-neg. isolates. Methicillin-susceptible and methicillin-resistant Staphylococcus aureus, coagulase-neg. Staphylococcus spp., Streptococcus spp., Listeria monocytogenes, Bacillus spp. and group JK corynebacteria were inhibited at concentrations equal to that of ciprofloxacin.
European Journal of Clinical Microbiology & Infectious Diseases published new progress about Bacteria. 105784-61-0 belongs to class piperazines, name is Temafloxacin hydrochloride, and the molecular formula is C21H19ClF3N3O3, Related Products of piperazines.
Referemce:
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Piperazines – an overview | ScienceDirect Topics