On May 10, 2001, Kabra, Bhagwati P. published a patent.Category: piperazines The title of the patent was Pharmaceutical compositions containing a fluoroquinolone antibiotic drug and xanthan gum. And the patent contained the following:
Pharmaceutical compositions containing a fluoroquinolone antibiotic drug, xanthan gum and a water-soluble calcium salt in an amount sufficient to make the fluoroquinolone antibiotic drug and xanthan gum compatible are disclosed. A pharmaceutical composition contained ciprofloxacin.HCl 0.35, xanthan gum 0.6, sodium sulfate 1.5, disodium edetate 0.05, BDAB 0.012, NaOH/HCl q.s. pH = 4.5, and water q.s. 100%. The experimental process involved the reaction of 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate(cas: 86393-32-0).Category: piperazines
The Article related to pharmaceutical fluoroquinolone antibiotic drug xanthan gum, Pharmaceuticals: Formulation and Compounding and other aspects.Category: piperazines
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics