On June 2, 2022, Zhang, Chen; Liao, Yuting; Ye, Fei; Tang, Pingming; Chen, Xiaogang; Lu, Yonghua; Gao, Qiu; Li, Yao; Ni, Jia; Yan, Pangke published a patent.Reference of tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate The title of the patent was Benzene ring derivative, and composition and pharmaceutical use thereof. And the patent contained the following:
Disclosed are a compound or a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, and an intermediate thereof, and the use thereof in AR or AR splicing mutant-related diseases such as cancer. The experimental process involved the reaction of tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate(cas: 1211568-27-2).Reference of tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate
The Article related to benzene ring derivative preparation treatment cancer disease, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Reference of tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics