On September 27, 2017, Beyzavi, Hudson; Mandal, Debashis; Strebl, Martin G.; Neumann, Constanze N.; D’Amato, Erica M.; Chen, Junting; Hooker, Jacob M.; Ritter, Tobias published an article.Formula: C12H16N2O2 The title of the article was 18F-Deoxyfluorination of Phenols via Ru π-Complexes. And the article contained the following:
The deficiency of robust and practical methods for 18F-radiofluorination is a bottleneck for positron emission tomog. (PET) tracer development. Here, we report the first transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atm., large substrate scope, and translatability to generate doses appropriate for PET imaging. The experimental process involved the reaction of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone(cas: 67914-60-7).Formula: C12H16N2O2
The Article related to transition metal assisted deoxyfluorination phenol ruthenium complex, crystal mol structure fluorophenyl ruthenium cyclopentenyl complex, radiofluorination phenol ruthenium complex and other aspects.Formula: C12H16N2O2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics