Yan, Longjia’s team published research in Tetrahedron Letters in 2019 | CAS: 127116-19-2

2-(4-(6-Chloro-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol(cas: 127116-19-2) belongs to piperazines. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines.COA of Formula: C11H17ClN4O

COA of Formula: C11H17ClN4OOn May 16, 2019 ,《Synthesis of N-pyrimidin[1,3,4]oxadiazoles and N-pyrimidin[1,3,4]-thiadiazoles from 1,3,4-oxadiazol-2-amines and 1,3,4-thiadiazol-2-amines via Pd-catalyzed heteroarylamination》 appeared in Tetrahedron Letters. The author of the article were Yan, Longjia; Deng, Minggao; Chen, Anchao; Li, Yongliang; Zhang, Wanzheng; Du, Zhi-yun; Dong, Chang-zhi; Meunier, Bernard; Chen, Huixiong. The article conveys some information:

An efficient and practical procedure was developed to prepare various N-pyrimidin[1,3,4]oxadiazole I (R1 = Cl, Ph, N-methylpiperazinyl, etc.; R2 = Me, Ph, C(O)OCH2CH3, etc.; X = O) and thiadiazole scaffolds I (X = S) from 1,3,4-oxadiazol-2-amines II (X = O) and 1,3,4-thiadiazol-2-amines II (X = S) with chloropyrimidines III via Pd-catalyzed heteroarylamination using a Buchwald-type coupling. The products of this reaction are otherwise difficult to access and could be used as building blocks in drug design. After reading the article, we found that the author used 2-(4-(6-Chloro-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol(cas: 127116-19-2COA of Formula: C11H17ClN4O)

2-(4-(6-Chloro-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol(cas: 127116-19-2) belongs to piperazines. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines.COA of Formula: C11H17ClN4O

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics