Name: 4-(Piperazin-1-yl)-1H-indoleOn May 9, 2013 ,《Structure-Based Fragment Screening Is Demonstrated To Be a Practical Lead Discovery Method for a Representative G-Protein-Coupled Receptor》 appeared in Journal of Medicinal Chemistry. The author of the article were Stevens, Benjamin D.. The article conveys some information:
A review. In this paper the author discusses the work of Christopher et al. who described a successful approach leading to the discovery of structurally novel β1 adrenoreceptor ligands driven exclusively by biophys. methods. A work that highlights the promise of such technol. for utilization in future GPCR lead discovery programs andprovides an appealing alternative to traditional approaches forreceptors where structural stabilization is possible. The experimental part of the paper was very detailed, including the reaction process of 4-(Piperazin-1-yl)-1H-indole(cas: 84807-09-0Name: 4-(Piperazin-1-yl)-1H-indole)
4-(Piperazin-1-yl)-1H-indole(cas: 84807-09-0) belongs to piperazines. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Name: 4-(Piperazin-1-yl)-1H-indole
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics