Liao, Rong; Chang, Yan published the artcile< A study on N-Boc-2,2-dimethyl-piperazine>, Recommanded Product: 3,3-Dimethylpiperazin-2-one, the main research area is dimethylpiperazine synthesis.
This paper studies the reaction temperature, ratio of reactants, and catalyst in order to get N-Boc-2,2-dimethyl-piperazine, a synthesis of ethylenediamine, Et 2-bromoisobutyrate, and di-tert-Bu dicarbonate. Experiment results suggest that the optimal condition is: first, using ethylenediamine and Et 2-bromoisobutyrate with a ratio of 3:1 to get intermediate product under 70°C; and then using the potassium carbonate to catalyze the intermediate product to get the final product.
Sichuan Huagong published new progress about 22476-74-0. 22476-74-0 belongs to class piperazines, and the molecular formula is C6H12N2O, Recommanded Product: 3,3-Dimethylpiperazin-2-one.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics