Luesse, Sarah B.; Wells, Gregg; Miller, Jeanne; Bolstad, Erin; Bergmeier, Stephen C.; McMills, Mark C.; Priestley, Nigel D.; Wright, Dennis L. published the artcile< Synthesis of a functionalized oxabicyclo[2.2.1]heptene-based chemical library>, HPLC of Formula: 197638-83-8, the main research area is chem library oxabicycloheptane preparation antibacterial agent.
The 7-oxabicyclo[2.2.1]heptene ring system is a common structural motif in many pharmacol. interesting mols. The authors recognized the potential to employ this highly oxygenated and conformationally-restricted scaffold in diversity-oriented method to generate a library of non-chiral but topol. complex compounds and the synthesis of the target compounds was achieved by an acetalization cyclcocondensation of aldehydes with (exo,exo)-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dimethanol. Herein, the authors report the synthesis and biol. evaluation of two 96-member tricyclic library containing the oxabicyclo[2.2.1]heptene framework [6,9-epoxy-2,4-benzodioxepin derivatives, conformationally restricted acetals].
Combinatorial Chemistry & High Throughput Screening published new progress about Acetalization. 197638-83-8 belongs to class piperazines, and the molecular formula is C16H22N2O3, HPLC of Formula: 197638-83-8.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics