Tabushi, Iwao; Shimokawa, Kazuhiro published an article in Journal of the American Chemical Society. The title of the article was 《Model approach to retinal pigments. Remarkable red shift due to proximal ammonium ion》.Name: 1-Methylpiperazine dihydrochloride The author mentioned the following in the article:
Retinal derivs, I and II, were prepared and the absorption characteristics of a series of retinal derivatives (I, II, III, IV, and V) were investigated as a model study for the remarkable red shift observed for the native retinal pigments such as rhodopsins or bacteriorhodopsins. Remarkable red shifts observed in the following 2 derivatives were interpreted mechanistically; in retinal N’-methylpiperidinium perchlorate, 526 nm in CHCl3, as the electrostatic destabilization of the ground state by the proximal NH4 with a loose counter-anion in a less polar solvent; and in III chloride, 497 nm in water, as the balance between the electrostatic destabilization and the twist of the chromophore. In addition to this study using 1-Methylpiperazine dihydrochloride, there are many other studies that have used 1-Methylpiperazine dihydrochloride(cas: 34352-59-5Name: 1-Methylpiperazine dihydrochloride) was used in this study.
1-Methylpiperazine dihydrochloride(cas: 34352-59-5) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), 1-methylpiperazine-1,4-diium tetrachloridozincate hemihydrate, 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug..Name: 1-Methylpiperazine dihydrochloride
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics