Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. 103-76-4, formula is C6H14N2O, Name is N-(2-Hydroxyethyl)piperazine. Piperazine exists as small alkaline deliquescent crystals with a saline taste. Recommanded Product: N-(2-Hydroxyethyl)piperazine.
Shalini;Johansen, Matt D.;Kremer, Laurent;Kumar, Vipan research published 《 Variedly connected 1,8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation》, the research content is summarized as follows. Synthesis, anti-mycobacterial and cytotoxic evaluation of 4-substituted 1,8-naphthalimide-7-chloroquinoline conjugates I [R = Br, piperidin-1-yl, 4-morpholinyl, 4-(2-hydroxyethyl)piperazin-1-yl; n = 2,3,4,6,8] and II connected through varied linkers in order to study their structure-activity relationship was reported. Simple alkyl chain linked conjugates showed better activity profiles without any cytotoxicity, while the inclusion of amide bond enhanced the cytotoxic tendency. Copmd. II [R1 = piperidin-1-yl; n = 6] proved to be the most potent and non-cytotoxic with MIC99 of 6.25 μg/mL and selectivity index of > 16. An interesting behavior of conjugates I and II in terms of activity and cytotoxicity was observed via switching over the nature of linker between two pharmacophores.
103-76-4, 1-(2-Hydroxyethyl)piperazine is a useful research compound. Its molecular formula is C6H14N2O and its molecular weight is 130.19 g/mol. The purity is usually 95%.
1-(2-Hydroxyethyl)piperazine is a chemical solvent that is used for the absorption of amines and other compounds. It has been shown to have a high affinity for acidic substances, which may be due to its ability to form hydrogen bonds with them. 1-(2-Hydroxyethyl)piperazine is also used in sample preparation for the analysis of amines and other compounds in fruit extracts. The solubility of 1-(2-Hydroxyethyl)piperazine depends on the experimental conditions, including pH, temperature, and pressure. FT-IR spectroscopy has been used to measure the vibrational modes of 1-(2-Hydroxyethyl)piperazine molecules. The IR spectrum revealed that this compound contains a hydroxyl group and two fatty acid chains with one or more hydroxyl groups at their terminal end. The nmr spectrum showed that 1-(2-Hydroxyethyl)piperazine contains an NH proton as well as, Recommanded Product: N-(2-Hydroxyethyl)piperazine
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics